1 Ocak 2015 Dergi makalesi Açık Erişim

Kordikanlioglu, Burcu; Simsek, Omer; Saris, Per E. J.

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  "@context": "https://schema.org/", 
  "@id": 83197, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Univ Pamukkale, Dept Food Engn, Denizli, Turkey", 
      "name": "Kordikanlioglu, Burcu"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Pamukkale, Dept Food Engn, Denizli, Turkey", 
      "name": "Simsek, Omer"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Helsinki, Dept Food & Environm Sci, Helsinki, Finland", 
      "name": "Saris, Per E. J."
    }
  ], 
  "datePublished": "2015-01-01", 
  "description": "In this study, nisin production of Lactococcus lactis N8 was optimized by independent variables of glucose, hemin and oxygen concentrations in fed-batch fermentation in which respiration of cells was stimulated with hemin. Response surface model was able to explain the changes of the nisin production of L. lactis N8 in fed-batch fermentation system with high fidelity (R-2 98%) and insignificant lack of fit. Accordingly, the equation developed indicated the optimum parameters for glucose, hemin, and dissolved oxygen were 8 g L-1 h(-1), 3 mu g mL(-1) and 40%, respectively. While 1711 IU mL(-1) nisin was produced by L. lactis N8 in control fed-batch fermentation, 5410 IU mL(-1) nisin production was achieved within the relevant optimum parameters where the respiration of cell was stimulated with hemin. Accordingly, nisin production was enhanced 3.1 fold in fed-batch fermentation using hemin. In conclusion the nisin production of L. lactis N8 was enhanced extensively as a result of increasing the biomass by stimulating the cell respiration with adding the hemin in the fed-batch fermentation. (C) 2015 American Institute of Chemical Engineers", 
  "headline": "Nisin Production of Lactococcus lactis N8 with Hemin-Stimulated Cell Respiration in Fed-Batch Fermentation System", 
  "identifier": 83197, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Nisin Production of Lactococcus lactis N8 with Hemin-Stimulated Cell Respiration in Fed-Batch Fermentation System", 
  "url": "https://aperta.ulakbim.gov.tr/record/83197"
}