1 Ocak 2014 Dergi makalesi Açık Erişim

Altug, Cevher; Buyukbayram, Muhammet; Kavas, Ozge; Yavuz, Muhsine Zeynep

Dublin Core

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  <dc:creator>Altug, Cevher</dc:creator>
  <dc:creator>Buyukbayram, Muhammet</dc:creator>
  <dc:creator>Kavas, Ozge</dc:creator>
  <dc:creator>Yavuz, Muhsine Zeynep</dc:creator>
  <dc:date>2014-01-01</dc:date>
  <dc:description>The present work describes a new protocol for the synthesis of 5-aminoisoxazoles using alpha-chlorooximes and 2-phenylsulfonyl acetonitrile via green chemistry routes. The titled 5-aminoisoxazoles 3 were further reacted with 4-nitrobenzoyl chloride to obtain 5-amidoisoxazoles with moderate yields. These heterocyclic compounds were tested in vitro MTT study to investigate inhibitive abilities to some cancer cell lines (C3a, L929, T98g and Mcf-7) and compounds 3a, 3c, 3e and 3h showed noticeable cytotoxic property against four cancer cell lines. (C) 2014 Elsevier Ltd. All rights reserved.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/63689</dc:identifier>
  <dc:identifier>oai:zenodo.org:63689</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>TETRAHEDRON 70(22) 3590-3594</dc:source>
  <dc:title>A green synthesis of new 3-aryl-4-phenylsulfonyl-5-aminoisoxazoles</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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