1 Ocak 2014 Dergi makalesi Açık Erişim

Altug, Cevher; Buyukbayram, Muhammet; Kavas, Ozge; Yavuz, Muhsine Zeynep

JSON

{
  "conceptrecid": "63688", 
  "created": "2021-03-16T01:43:48.550973+00:00", 
  "doi": "10.1016/j.tet.2014.03.106", 
  "files": [
    {
      "bucket": "1b25ecd5-a36c-4557-9581-fdc106e69790", 
      "checksum": "md5:8defc345cde68e7a3f1fdcf6d166d126", 
      "key": "bib-f7dddd28-e80a-4c1c-ac3c-af3611da6904.txt", 
      "links": {
        "self": "https://aperta.ulakbim.gov.tr/api/files/1b25ecd5-a36c-4557-9581-fdc106e69790/bib-f7dddd28-e80a-4c1c-ac3c-af3611da6904.txt"
      }, 
      "size": 157, 
      "type": "txt"
    }
  ], 
  "id": 63689, 
  "links": {
    "badge": "https://aperta.ulakbim.gov.tr/badge/doi/10.1016/j.tet.2014.03.106.svg", 
    "bucket": "https://aperta.ulakbim.gov.tr/api/files/1b25ecd5-a36c-4557-9581-fdc106e69790", 
    "doi": "https://doi.org/10.1016/j.tet.2014.03.106", 
    "html": "https://aperta.ulakbim.gov.tr/record/63689", 
    "latest": "https://aperta.ulakbim.gov.tr/api/records/63689", 
    "latest_html": "https://aperta.ulakbim.gov.tr/record/63689"
  }, 
  "metadata": {
    "access_right": "open", 
    "access_right_category": "success", 
    "communities": [
      {
        "id": "tubitak-destekli-proje-yayinlari"
      }
    ], 
    "creators": [
      {
        "affiliation": "Abant Izzet Baysal Univ, Dept Chem, TR-14280 Bolu, Turkey", 
        "name": "Altug, Cevher"
      }, 
      {
        "affiliation": "Abant Izzet Baysal Univ, Dept Chem, TR-14280 Bolu, Turkey", 
        "name": "Buyukbayram, Muhammet"
      }, 
      {
        "affiliation": "Abant Izzet Baysal Univ, Dept Chem, TR-14280 Bolu, Turkey", 
        "name": "Kavas, Ozge"
      }, 
      {
        "affiliation": "Abant Izzet Baysal Univ, Fac Med, Dept Med Pharmacol, TR-14280 Bolu, Turkey", 
        "name": "Yavuz, Muhsine Zeynep"
      }
    ], 
    "description": "The present work describes a new protocol for the synthesis of 5-aminoisoxazoles using alpha-chlorooximes and 2-phenylsulfonyl acetonitrile via green chemistry routes. The titled 5-aminoisoxazoles 3 were further reacted with 4-nitrobenzoyl chloride to obtain 5-amidoisoxazoles with moderate yields. These heterocyclic compounds were tested in vitro MTT study to investigate inhibitive abilities to some cancer cell lines (C3a, L929, T98g and Mcf-7) and compounds 3a, 3c, 3e and 3h showed noticeable cytotoxic property against four cancer cell lines. (C) 2014 Elsevier Ltd. All rights reserved.", 
    "doi": "10.1016/j.tet.2014.03.106", 
    "has_grant": false, 
    "journal": {
      "issue": "22", 
      "pages": "3590-3594", 
      "title": "TETRAHEDRON", 
      "volume": "70"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2014-01-01", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "63689"
          }, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "63688"
          }
        }
      ]
    }, 
    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
    }, 
    "title": "A green synthesis of new 3-aryl-4-phenylsulfonyl-5-aminoisoxazoles"
  }, 
  "owners": [
    1
  ], 
  "revision": 1, 
  "stats": {
    "downloads": 12.0, 
    "unique_downloads": 12.0, 
    "unique_views": 40.0, 
    "version_downloads": 12.0, 
    "version_unique_downloads": 12.0, 
    "version_unique_views": 38.0, 
    "version_views": 43.0, 
    "version_volume": 1884.0, 
    "views": 45.0, 
    "volume": 1884.0
  }, 
  "updated": "2021-03-16T01:43:48.596920+00:00"
}