Dergi makalesi Açık Erişim
Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ozkilic, Hayal; Yilmaz, Ferda; Hosgor-Limoncu, Mine
<?xml version='1.0' encoding='UTF-8'?> <record xmlns="http://www.loc.gov/MARC21/slim"> <leader>00000nam##2200000uu#4500</leader> <datafield tag="245" ind1=" " ind2=" "> <subfield code="a">Evaluation of Tc-99m-amoxicillin sodium as an infection imaging agent in bacterially infected and sterile inflamed rats</subfield> </datafield> <datafield tag="909" ind1="C" ind2="4"> <subfield code="p">JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY</subfield> <subfield code="v">308</subfield> <subfield code="n">3</subfield> <subfield code="c">995-1004</subfield> </datafield> <controlfield tag="001">55197</controlfield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="520" ind1=" " ind2=" "> <subfield code="a">Bacterial infection is one of the major causes of morbidity and mortality especially in developing countries. The aim of this study was to develop a new radiopharmaceutical for imaging infection. The labeling conditions were optimized, and lyophilized kits were developed for instant preparing. The stability of Tc-99m-AMOX in human serum was identified, sterility and pyrogenicity of the radiopharmaceutical were estimated, gamma scintigraphy and in vivo biodistribution with infected rats were investigated. The promising properties of Tc-99m-AMOX combined with the development of reliable and instant lyophilized kit afford the opportunity of inflammatory process imaging.</subfield> </datafield> <datafield tag="650" ind1="1" ind2="7"> <subfield code="2">opendefinition.org</subfield> <subfield code="a">cc-by</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey</subfield> <subfield code="a">Caglayan-Orumlu, Oya</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey</subfield> <subfield code="a">Asikoglu, Makbule</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Dept Nucl Med, Fac Med, Izmir, Turkey</subfield> <subfield code="a">Ozkilic, Hayal</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Dept Pharmaceut Microbiol, Fac Pharm, Izmir, Turkey</subfield> <subfield code="a">Yilmaz, Ferda</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Dept Pharmaceut Microbiol, Fac Pharm, Izmir, Turkey</subfield> <subfield code="a">Hosgor-Limoncu, Mine</subfield> </datafield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="b">article</subfield> <subfield code="a">publication</subfield> </datafield> <datafield tag="542" ind1=" " ind2=" "> <subfield code="l">open</subfield> </datafield> <datafield tag="100" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey</subfield> <subfield code="a">Ilem-Ozdemir, Derya</subfield> </datafield> <datafield tag="260" ind1=" " ind2=" "> <subfield code="c">2016-01-01</subfield> </datafield> <controlfield tag="005">20210315234748.0</controlfield> <datafield tag="909" ind1="C" ind2="O"> <subfield code="o">oai:zenodo.org:55197</subfield> <subfield code="p">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="z">md5:b807655022bc9fb03a545e4da9146152</subfield> <subfield code="s">294</subfield> <subfield code="u">https://aperta.ulakbim.gov.trrecord/55197/files/bib-68205fd6-eef3-42ea-89b9-8d8e9e504c1d.txt</subfield> </datafield> <datafield tag="540" ind1=" " ind2=" "> <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield> <subfield code="a">Creative Commons Attribution</subfield> </datafield> <datafield tag="024" ind1=" " ind2=" "> <subfield code="a">10.1007/s10967-015-4516-4</subfield> <subfield code="2">doi</subfield> </datafield> </record>
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