1 Ocak 2016 Dergi makalesi Açık Erişim

Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ozkilic, Hayal; Yilmaz, Ferda; Hosgor-Limoncu, Mine

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{
  "@context": "https://schema.org/", 
  "@id": 55197, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey", 
      "name": "Ilem-Ozdemir, Derya"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey", 
      "name": "Caglayan-Orumlu, Oya"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey", 
      "name": "Asikoglu, Makbule"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Dept Nucl Med, Fac Med, Izmir, Turkey", 
      "name": "Ozkilic, Hayal"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Dept Pharmaceut Microbiol, Fac Pharm, Izmir, Turkey", 
      "name": "Yilmaz, Ferda"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Dept Pharmaceut Microbiol, Fac Pharm, Izmir, Turkey", 
      "name": "Hosgor-Limoncu, Mine"
    }
  ], 
  "datePublished": "2016-01-01", 
  "description": "Bacterial infection is one of the major causes of morbidity and mortality especially in developing countries. The aim of this study was to develop a new radiopharmaceutical for imaging infection. The labeling conditions were optimized, and lyophilized kits were developed for instant preparing. The stability of Tc-99m-AMOX in human serum was identified, sterility and pyrogenicity of the radiopharmaceutical were estimated, gamma scintigraphy and in vivo biodistribution with infected rats were investigated. The promising properties of Tc-99m-AMOX combined with the development of reliable and instant lyophilized kit afford the opportunity of inflammatory process imaging.", 
  "headline": "Evaluation of Tc-99m-amoxicillin sodium as an infection imaging agent in bacterially infected and sterile inflamed rats", 
  "identifier": 55197, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Evaluation of Tc-99m-amoxicillin sodium as an infection imaging agent in bacterially infected and sterile inflamed rats", 
  "url": "https://aperta.ulakbim.gov.tr/record/55197"
}