1 Ocak 2016 Dergi makalesi Açık Erişim

Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ozkilic, Hayal; Yilmaz, Ferda; Hosgor-Limoncu, Mine

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/55197</identifier>
  <creators>
    <creator>
      <creatorName>Ilem-Ozdemir, Derya</creatorName>
      <givenName>Derya</givenName>
      <familyName>Ilem-Ozdemir</familyName>
      <affiliation>Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Caglayan-Orumlu, Oya</creatorName>
      <givenName>Oya</givenName>
      <familyName>Caglayan-Orumlu</familyName>
      <affiliation>Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Asikoglu, Makbule</creatorName>
      <givenName>Makbule</givenName>
      <familyName>Asikoglu</familyName>
      <affiliation>Ege Univ, Fac Pharm, Dept Radiopharm, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozkilic, Hayal</creatorName>
      <givenName>Hayal</givenName>
      <familyName>Ozkilic</familyName>
      <affiliation>Ege Univ, Dept Nucl Med, Fac Med, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz, Ferda</creatorName>
      <givenName>Ferda</givenName>
      <familyName>Yilmaz</familyName>
      <affiliation>Ege Univ, Dept Pharmaceut Microbiol, Fac Pharm, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Hosgor-Limoncu, Mine</creatorName>
      <givenName>Mine</givenName>
      <familyName>Hosgor-Limoncu</familyName>
      <affiliation>Ege Univ, Dept Pharmaceut Microbiol, Fac Pharm, Izmir, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Evaluation Of Tc-99M-Amoxicillin Sodium As An Infection Imaging Agent In Bacterially Infected And Sterile Inflamed Rats</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2016</publicationYear>
  <dates>
    <date dateType="Issued">2016-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/55197</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1007/s10967-015-4516-4</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Bacterial infection is one of the major causes of morbidity and mortality especially in developing countries. The aim of this study was to develop a new radiopharmaceutical for imaging infection. The labeling conditions were optimized, and lyophilized kits were developed for instant preparing. The stability of Tc-99m-AMOX in human serum was identified, sterility and pyrogenicity of the radiopharmaceutical were estimated, gamma scintigraphy and in vivo biodistribution with infected rats were investigated. The promising properties of Tc-99m-AMOX combined with the development of reliable and instant lyophilized kit afford the opportunity of inflammatory process imaging.</description>
  </descriptions>
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