Dergi makalesi Açık Erişim
Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ozkilic, Hayal; Yilmaz, Ferda; Hosgor-Limoncu, Mine
{ "DOI": "10.1007/s10967-015-4516-4", "abstract": "Bacterial infection is one of the major causes of morbidity and mortality especially in developing countries. The aim of this study was to develop a new radiopharmaceutical for imaging infection. The labeling conditions were optimized, and lyophilized kits were developed for instant preparing. The stability of Tc-99m-AMOX in human serum was identified, sterility and pyrogenicity of the radiopharmaceutical were estimated, gamma scintigraphy and in vivo biodistribution with infected rats were investigated. The promising properties of Tc-99m-AMOX combined with the development of reliable and instant lyophilized kit afford the opportunity of inflammatory process imaging.", "author": [ { "family": "Ilem-Ozdemir", "given": " Derya" }, { "family": "Caglayan-Orumlu", "given": " Oya" }, { "family": "Asikoglu", "given": " Makbule" }, { "family": "Ozkilic", "given": " Hayal" }, { "family": "Yilmaz", "given": " Ferda" }, { "family": "Hosgor-Limoncu", "given": " Mine" } ], "container_title": "JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY", "id": "55197", "issue": "3", "issued": { "date-parts": [ [ 2016, 1, 1 ] ] }, "page": "995-1004", "title": "Evaluation of Tc-99m-amoxicillin sodium as an infection imaging agent in bacterially infected and sterile inflamed rats", "type": "article-journal", "volume": "308" }
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