Dergi makalesi Açık Erişim
Karatum, Onuralp; Aria, Mohammad Mohammadi; Eren, Guncem Ozgun; Yildiz, Erdost; Melikov, Rustamzhon; Srivastava, Shashi Bhushan; Surme, Saliha; Dogru, Itir Bakis; Jalali, Houman Bahmani; Ulgut, Burak; Sahin, Afsun; Kavakli, Ibrahim Halil; Nizamoglu, Sedat
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"affiliation": "Koc Univ, Dept Elect & Elect Engn, Istanbul, Turkey",
"name": "Karatum, Onuralp"
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{
"affiliation": "Koc Univ, Dept Biomed Sci & Engn, Istanbul, Turkey",
"name": "Aria, Mohammad Mohammadi"
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{
"affiliation": "Koc Univ, Dept Biomed Sci & Engn, Istanbul, Turkey",
"name": "Eren, Guncem Ozgun"
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{
"affiliation": "Koc Univ, Res Ctr Translat Med, Istanbul, Turkey",
"name": "Yildiz, Erdost"
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{
"affiliation": "Koc Univ, Dept Elect & Elect Engn, Istanbul, Turkey",
"name": "Melikov, Rustamzhon"
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{
"affiliation": "Koc Univ, Dept Elect & Elect Engn, Istanbul, Turkey",
"name": "Srivastava, Shashi Bhushan"
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{
"affiliation": "Koc Univ, Dept Mol Biol & Genet, Istanbul, Turkey",
"name": "Surme, Saliha"
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{
"affiliation": "Koc Univ, Dept Biomed Sci & Engn, Istanbul, Turkey",
"name": "Dogru, Itir Bakis"
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{
"affiliation": "Koc Univ, Dept Biomed Sci & Engn, Istanbul, Turkey",
"name": "Jalali, Houman Bahmani"
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{
"affiliation": "Brikent Univ, Dept Chem, Ankara, Turkey",
"name": "Ulgut, Burak"
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{
"name": "Sahin, Afsun"
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{
"affiliation": "Koc Univ, Dept Mol Biol & Genet, Istanbul, Turkey",
"name": "Kavakli, Ibrahim Halil"
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"name": "Nizamoglu, Sedat"
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"description": "Light-activated biointerfaces provide a non-genetic route for effective control of neural activity. InP quantum dots (QDs) have a high potential for such biomedical applications due to their uniquely tunable electronic properties, photostability, toxic-heavy-metal-free content, heterostructuring, and solution-processing ability. However, the effect of QD nanostructure and biointerface architecture on the photoelectrical cellular interfacing remained unexplored. Here, we unravel the control of the photoelectrical response of InP QD-based biointerfaces via nanoengineering from QD to device-level. At QD level, thin ZnS shell growth (similar to 0.65 nm) enhances the current level of biointerfaces over an order of magnitude with respect to only InP core QDs. At device-level, band alignment engineering allows for the bidirectional photoelectrochemical current generation, which enables light-induced temporally precise and rapidly reversible action potential generation and hyperpolarization on primary hippocampal neurons. Our findings show that nanoengineering QD-based biointerfaces hold great promise for next-generation neurostimulation devices.",
"doi": "10.3389/fnins.2021.652608",
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"journal": {
"title": "FRONTIERS IN NEUROSCIENCE",
"volume": "15"
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"title": "Nanoengineering InP Quantum Dot-Based Photoactive Biointerfaces for Optical Control of Neurons"
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