1 Ocak 2021 Dergi makalesi Açık Erişim

Gozalan, Aysegul; Unaldi, Ozlem; Guldemir, Dilek; Aydogan, Sibel; Kuzucu, Cigdem; Cakirlar, Fatma Koksal; Acikgoz, Ziya Cibali; Durmaz, Riza

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{
  "@context": "https://schema.org/", 
  "@id": 233202, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Alanya Alaaddin Keykubat Univ, Fac Med, Dept Med Microbiol, TR-07400 Antalya, Turkey", 
      "name": "Gozalan, Aysegul"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Minist Hlth, Natl Mol Microbiol Reference Lab, Publ Hlth Gen Directorate, Ankara, Turkey", 
      "name": "Unaldi, Ozlem"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Minist Hlth, Natl Mol Microbiol Reference Lab, Publ Hlth Gen Directorate, Ankara, Turkey", 
      "name": "Guldemir, Dilek"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Minist Hlth, Dept Med Microbiol, Ankara City Hosp, Ankara, Turkey", 
      "name": "Aydogan, Sibel"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Tinaztepe Izmir Univ, Fac Med, Dept Med Microbiol, Izmir, Turkey", 
      "name": "Kuzucu, Cigdem"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Med Microbiol, Istanbul, Turkey", 
      "name": "Cakirlar, Fatma Koksal"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Yildirim Beyazit Univ, Fac Med, Dept Med Microbiol, Ankara, Turkey", 
      "name": "Acikgoz, Ziya Cibali"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Yildirim Beyazit Univ, Fac Med, Dept Med Microbiol, Ankara, Turkey", 
      "name": "Durmaz, Riza"
    }
  ], 
  "datePublished": "2021-01-01", 
  "description": "We aimed to investigate the clonal relationships, common sequence types, and carbapenemase genes in 177 non-repetitive blood culture isolates of Acinetobacter baumannii collected from patients at three university hospitals in Turkey in 2016. Molecular epidemiological characteristics of the isolates were examined using pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing (MLST) (Pasteur scheme-cpn60, fusA, gltA, pyrG, recA, rplB, and rpoB). Multiplex PCR was used to investigate the carbapenemase genes, including bla(OXA-23-like),bla(OXA-24-like), bla(OXA-48-like), bla(OXA-58-like), bla(IMP), bla(VIM) and bla(NDm). PFGE genotyping yielded 92 pulsotypes with a clustering ratio of 69.7%. As per a >= 85% similarity coefficient, 159 (90.9%) isolates were found to be clonally related. The bla(OXA-)(23-like) and bla(OXA-)(58)-like genes were identified in 100% and 28.2% of the isolates, respectively. The bla(NDM) gene was identified in two isolates. The MLST analysis included 54 isolates with different pulsotypes, and 29 sequence types (STs). Most of the isolates (n = 36) belonged to the clonal complex (CC)2, one isolate belonged to CC1, and one isolate belonged to CC164. Sixteen new STs (ST1235-ST1250) were identified. Identifying both global ST2 and a large number of new STs, revealed high genetic diversity in A. baumannii isolates in the study population.", 
  "headline": "Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Blood Culture Isolates from Three Hospitals in Turkey", 
  "identifier": 233202, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Blood Culture Isolates from Three Hospitals in Turkey", 
  "url": "https://aperta.ulakbim.gov.tr/record/233202"
}