1 Ocak 2021 Dergi makalesi Açık Erişim

Gozalan, Aysegul; Unaldi, Ozlem; Guldemir, Dilek; Aydogan, Sibel; Kuzucu, Cigdem; Cakirlar, Fatma Koksal; Acikgoz, Ziya Cibali; Durmaz, Riza

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    "creators": [
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        "affiliation": "Alanya Alaaddin Keykubat Univ, Fac Med, Dept Med Microbiol, TR-07400 Antalya, Turkey", 
        "name": "Gozalan, Aysegul"
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        "affiliation": "Minist Hlth, Natl Mol Microbiol Reference Lab, Publ Hlth Gen Directorate, Ankara, Turkey", 
        "name": "Unaldi, Ozlem"
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        "affiliation": "Minist Hlth, Natl Mol Microbiol Reference Lab, Publ Hlth Gen Directorate, Ankara, Turkey", 
        "name": "Guldemir, Dilek"
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      {
        "affiliation": "Minist Hlth, Dept Med Microbiol, Ankara City Hosp, Ankara, Turkey", 
        "name": "Aydogan, Sibel"
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      {
        "affiliation": "Tinaztepe Izmir Univ, Fac Med, Dept Med Microbiol, Izmir, Turkey", 
        "name": "Kuzucu, Cigdem"
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      {
        "affiliation": "Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Med Microbiol, Istanbul, Turkey", 
        "name": "Cakirlar, Fatma Koksal"
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      {
        "affiliation": "Yildirim Beyazit Univ, Fac Med, Dept Med Microbiol, Ankara, Turkey", 
        "name": "Acikgoz, Ziya Cibali"
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      {
        "affiliation": "Yildirim Beyazit Univ, Fac Med, Dept Med Microbiol, Ankara, Turkey", 
        "name": "Durmaz, Riza"
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    "description": "We aimed to investigate the clonal relationships, common sequence types, and carbapenemase genes in 177 non-repetitive blood culture isolates of Acinetobacter baumannii collected from patients at three university hospitals in Turkey in 2016. Molecular epidemiological characteristics of the isolates were examined using pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing (MLST) (Pasteur scheme-cpn60, fusA, gltA, pyrG, recA, rplB, and rpoB). Multiplex PCR was used to investigate the carbapenemase genes, including bla(OXA-23-like),bla(OXA-24-like), bla(OXA-48-like), bla(OXA-58-like), bla(IMP), bla(VIM) and bla(NDm). PFGE genotyping yielded 92 pulsotypes with a clustering ratio of 69.7%. As per a >= 85% similarity coefficient, 159 (90.9%) isolates were found to be clonally related. The bla(OXA-)(23-like) and bla(OXA-)(58)-like genes were identified in 100% and 28.2% of the isolates, respectively. The bla(NDM) gene was identified in two isolates. The MLST analysis included 54 isolates with different pulsotypes, and 29 sequence types (STs). Most of the isolates (n = 36) belonged to the clonal complex (CC)2, one isolate belonged to CC1, and one isolate belonged to CC164. Sixteen new STs (ST1235-ST1250) were identified. Identifying both global ST2 and a large number of new STs, revealed high genetic diversity in A. baumannii isolates in the study population.", 
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      "issue": "3", 
      "pages": "200-208", 
      "title": "JAPANESE JOURNAL OF INFECTIOUS DISEASES", 
      "volume": "74"
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    "publication_date": "2021-01-01", 
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    "title": "Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Blood Culture Isolates from Three Hospitals in Turkey"
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