1 Ocak 2018 Dergi makalesi Açık Erişim

Narter, Fehmi; Diren, Ayca; Kafkasli, Alper; Eronat, Allison P.; Seyhan, M. Fatih; Yilmaz-Aydogan, Hulya; Sarikaya, Sukran; Hatipoglu, Seda Damla; Sarica, Kemal; Ozturk, Oguz

Dublin Core

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  <dc:creator>Narter, Fehmi</dc:creator>
  <dc:creator>Diren, Ayca</dc:creator>
  <dc:creator>Kafkasli, Alper</dc:creator>
  <dc:creator>Eronat, Allison P.</dc:creator>
  <dc:creator>Seyhan, M. Fatih</dc:creator>
  <dc:creator>Yilmaz-Aydogan, Hulya</dc:creator>
  <dc:creator>Sarikaya, Sukran</dc:creator>
  <dc:creator>Hatipoglu, Seda Damla</dc:creator>
  <dc:creator>Sarica, Kemal</dc:creator>
  <dc:creator>Ozturk, Oguz</dc:creator>
  <dc:date>2018-01-01</dc:date>
  <dc:description>One of the many properties of propolis, a gift of nature, is that it is a potent antioxidant agent, which has been shown to be a miracle-worker in many different diseases. In this study, its possible protective and reversing effects against hiperoxaluria was investigated in a rat model in comparison with verapamil In all 5 groups (Total n=76), aside from the control, hiperoxaluria was induced with continuous ethylene glycol (EG) administration. The others received EG only, 50 mg/kg propolis, 100 mg/kg propolis and 1 mg/kg verapamil To estimate the antioxidant/oxidant status in the tissue and serum samples, catalase (CAT), superoxide dismutase (SOD), total glutathione (GSH), nitric oxide (NO), malonyl dialdehyde (MDA) and total anti-oxidant capacity (T-AOC) were measured after 7 and 28 days. In the early phase, serum T-AOC levels were significantly elevated in the EG+P100 (p=0.0062) compared to the control, while in the late phase, it was elevated in the EG+P50 (p=0.037) and EG+V (p=0.009) compared to the EG only group. Propolis administration was observed to dramatically decrease crystal deposition (p&lt;0.0001) and was more effective in the prevention of oxalate-induced renal injury than verapamil Propolis being a natural product with almost none adverse effects elevates its value as a future approach to urolithiasis.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/93359</dc:identifier>
  <dc:identifier>oai:zenodo.org:93359</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>RECORDS OF NATURAL PRODUCTS 12(5) 445-459</dc:source>
  <dc:title>Anatolian Propolis Prevents Oxalate Kidney Stones: Dramatic Reduction of Crystal Deposition in Ethylene-Glycol-Induced Rat Model</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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