1 Ocak 2018 Dergi makalesi Açık Erişim

Narter, Fehmi; Diren, Ayca; Kafkasli, Alper; Eronat, Allison P.; Seyhan, M. Fatih; Yilmaz-Aydogan, Hulya; Sarikaya, Sukran; Hatipoglu, Seda Damla; Sarica, Kemal; Ozturk, Oguz

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/93359</identifier>
  <creators>
    <creator>
      <creatorName>Narter, Fehmi</creatorName>
      <givenName>Fehmi</givenName>
      <familyName>Narter</familyName>
      <affiliation>Kartal Dr Lutfi Kirdar Res &amp; Training Hosp, Dept Urol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Diren, Ayca</creatorName>
      <givenName>Ayca</givenName>
      <familyName>Diren</familyName>
      <affiliation>Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kafkasli, Alper</creatorName>
      <givenName>Alper</givenName>
      <familyName>Kafkasli</familyName>
      <affiliation>Istanbul Yeni Yuzyil Univ, Dept Urol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Eronat, Allison P.</creatorName>
      <givenName>Allison P.</givenName>
      <familyName>Eronat</familyName>
      <affiliation>Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Seyhan, M. Fatih</creatorName>
      <givenName>M. Fatih</givenName>
      <familyName>Seyhan</familyName>
      <affiliation>Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz-Aydogan, Hulya</creatorName>
      <givenName>Hulya</givenName>
      <familyName>Yilmaz-Aydogan</familyName>
      <affiliation>Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sarikaya, Sukran</creatorName>
      <givenName>Sukran</givenName>
      <familyName>Sarikaya</familyName>
      <affiliation>Kartal Dr Lutfi Kirdar Res &amp; Training Hosp, Dept Pathol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Hatipoglu, Seda Damla</creatorName>
      <givenName>Seda Damla</givenName>
      <familyName>Hatipoglu</familyName>
      <affiliation>TUBITAK UME Natl Metrol Inst, Chem Grp, Reference Mat Lab, Gebze, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sarica, Kemal</creatorName>
      <givenName>Kemal</givenName>
      <familyName>Sarica</familyName>
      <affiliation>Kartal Dr Lutfi Kirdar Res &amp; Training Hosp, Dept Urol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozturk, Oguz</creatorName>
      <givenName>Oguz</givenName>
      <familyName>Ozturk</familyName>
      <affiliation>Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Anatolian Propolis Prevents Oxalate Kidney Stones: Dramatic Reduction Of Crystal Deposition In Ethylene-Glycol-Induced Rat Model</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2018</publicationYear>
  <dates>
    <date dateType="Issued">2018-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/93359</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.25135/rnp.48.17.11.075</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">One of the many properties of propolis, a gift of nature, is that it is a potent antioxidant agent, which has been shown to be a miracle-worker in many different diseases. In this study, its possible protective and reversing effects against hiperoxaluria was investigated in a rat model in comparison with verapamil In all 5 groups (Total n=76), aside from the control, hiperoxaluria was induced with continuous ethylene glycol (EG) administration. The others received EG only, 50 mg/kg propolis, 100 mg/kg propolis and 1 mg/kg verapamil To estimate the antioxidant/oxidant status in the tissue and serum samples, catalase (CAT), superoxide dismutase (SOD), total glutathione (GSH), nitric oxide (NO), malonyl dialdehyde (MDA) and total anti-oxidant capacity (T-AOC) were measured after 7 and 28 days. In the early phase, serum T-AOC levels were significantly elevated in the EG+P100 (p=0.0062) compared to the control, while in the late phase, it was elevated in the EG+P50 (p=0.037) and EG+V (p=0.009) compared to the EG only group. Propolis administration was observed to dramatically decrease crystal deposition (p&amp;lt;0.0001) and was more effective in the prevention of oxalate-induced renal injury than verapamil Propolis being a natural product with almost none adverse effects elevates its value as a future approach to urolithiasis.</description>
  </descriptions>
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