1 Ocak 2018 Dergi makalesi Açık Erişim

Narter, Fehmi; Diren, Ayca; Kafkasli, Alper; Eronat, Allison P.; Seyhan, M. Fatih; Yilmaz-Aydogan, Hulya; Sarikaya, Sukran; Hatipoglu, Seda Damla; Sarica, Kemal; Ozturk, Oguz

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    "creators": [
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        "affiliation": "Kartal Dr Lutfi Kirdar Res & Training Hosp, Dept Urol, Istanbul, Turkey", 
        "name": "Narter, Fehmi"
      }, 
      {
        "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
        "name": "Diren, Ayca"
      }, 
      {
        "affiliation": "Istanbul Yeni Yuzyil Univ, Dept Urol, Istanbul, Turkey", 
        "name": "Kafkasli, Alper"
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      {
        "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
        "name": "Eronat, Allison P."
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      {
        "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
        "name": "Seyhan, M. Fatih"
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      {
        "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
        "name": "Yilmaz-Aydogan, Hulya"
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      {
        "affiliation": "Kartal Dr Lutfi Kirdar Res & Training Hosp, Dept Pathol, Istanbul, Turkey", 
        "name": "Sarikaya, Sukran"
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      {
        "affiliation": "TUBITAK UME Natl Metrol Inst, Chem Grp, Reference Mat Lab, Gebze, Turkey", 
        "name": "Hatipoglu, Seda Damla"
      }, 
      {
        "affiliation": "Kartal Dr Lutfi Kirdar Res & Training Hosp, Dept Urol, Istanbul, Turkey", 
        "name": "Sarica, Kemal"
      }, 
      {
        "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
        "name": "Ozturk, Oguz"
      }
    ], 
    "description": "One of the many properties of propolis, a gift of nature, is that it is a potent antioxidant agent, which has been shown to be a miracle-worker in many different diseases. In this study, its possible protective and reversing effects against hiperoxaluria was investigated in a rat model in comparison with verapamil In all 5 groups (Total n=76), aside from the control, hiperoxaluria was induced with continuous ethylene glycol (EG) administration. The others received EG only, 50 mg/kg propolis, 100 mg/kg propolis and 1 mg/kg verapamil To estimate the antioxidant/oxidant status in the tissue and serum samples, catalase (CAT), superoxide dismutase (SOD), total glutathione (GSH), nitric oxide (NO), malonyl dialdehyde (MDA) and total anti-oxidant capacity (T-AOC) were measured after 7 and 28 days. In the early phase, serum T-AOC levels were significantly elevated in the EG+P100 (p=0.0062) compared to the control, while in the late phase, it was elevated in the EG+P50 (p=0.037) and EG+V (p=0.009) compared to the EG only group. Propolis administration was observed to dramatically decrease crystal deposition (p<0.0001) and was more effective in the prevention of oxalate-induced renal injury than verapamil Propolis being a natural product with almost none adverse effects elevates its value as a future approach to urolithiasis.", 
    "doi": "10.25135/rnp.48.17.11.075", 
    "has_grant": false, 
    "journal": {
      "issue": "5", 
      "pages": "445-459", 
      "title": "RECORDS OF NATURAL PRODUCTS", 
      "volume": "12"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2018-01-01", 
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    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
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    "title": "Anatolian Propolis Prevents Oxalate Kidney Stones: Dramatic Reduction of Crystal Deposition in Ethylene-Glycol-Induced Rat Model"
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