1 Ocak 2018 Dergi makalesi Açık Erişim

Narter, Fehmi; Diren, Ayca; Kafkasli, Alper; Eronat, Allison P.; Seyhan, M. Fatih; Yilmaz-Aydogan, Hulya; Sarikaya, Sukran; Hatipoglu, Seda Damla; Sarica, Kemal; Ozturk, Oguz

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{
  "@context": "https://schema.org/", 
  "@id": 93359, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Kartal Dr Lutfi Kirdar Res & Training Hosp, Dept Urol, Istanbul, Turkey", 
      "name": "Narter, Fehmi"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
      "name": "Diren, Ayca"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Yeni Yuzyil Univ, Dept Urol, Istanbul, Turkey", 
      "name": "Kafkasli, Alper"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
      "name": "Eronat, Allison P."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
      "name": "Seyhan, M. Fatih"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
      "name": "Yilmaz-Aydogan, Hulya"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Kartal Dr Lutfi Kirdar Res & Training Hosp, Dept Pathol, Istanbul, Turkey", 
      "name": "Sarikaya, Sukran"
    }, 
    {
      "@type": "Person", 
      "affiliation": "TUBITAK UME Natl Metrol Inst, Chem Grp, Reference Mat Lab, Gebze, Turkey", 
      "name": "Hatipoglu, Seda Damla"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Kartal Dr Lutfi Kirdar Res & Training Hosp, Dept Urol, Istanbul, Turkey", 
      "name": "Sarica, Kemal"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Istanbul Univ, Inst Expt Med, Dept Mol Med, Istanbul, Turkey", 
      "name": "Ozturk, Oguz"
    }
  ], 
  "datePublished": "2018-01-01", 
  "description": "One of the many properties of propolis, a gift of nature, is that it is a potent antioxidant agent, which has been shown to be a miracle-worker in many different diseases. In this study, its possible protective and reversing effects against hiperoxaluria was investigated in a rat model in comparison with verapamil In all 5 groups (Total n=76), aside from the control, hiperoxaluria was induced with continuous ethylene glycol (EG) administration. The others received EG only, 50 mg/kg propolis, 100 mg/kg propolis and 1 mg/kg verapamil To estimate the antioxidant/oxidant status in the tissue and serum samples, catalase (CAT), superoxide dismutase (SOD), total glutathione (GSH), nitric oxide (NO), malonyl dialdehyde (MDA) and total anti-oxidant capacity (T-AOC) were measured after 7 and 28 days. In the early phase, serum T-AOC levels were significantly elevated in the EG+P100 (p=0.0062) compared to the control, while in the late phase, it was elevated in the EG+P50 (p=0.037) and EG+V (p=0.009) compared to the EG only group. Propolis administration was observed to dramatically decrease crystal deposition (p<0.0001) and was more effective in the prevention of oxalate-induced renal injury than verapamil Propolis being a natural product with almost none adverse effects elevates its value as a future approach to urolithiasis.", 
  "headline": "Anatolian Propolis Prevents Oxalate Kidney Stones: Dramatic Reduction of Crystal Deposition in Ethylene-Glycol-Induced Rat Model", 
  "identifier": 93359, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Anatolian Propolis Prevents Oxalate Kidney Stones: Dramatic Reduction of Crystal Deposition in Ethylene-Glycol-Induced Rat Model", 
  "url": "https://aperta.ulakbim.gov.tr/record/93359"
}