1 Ocak 2015 Dergi makalesi Açık Erişim

Bagdas, Deniz; Targowska-Duda, Katarzyna M.; Lopez, Jhon J.; Perez, Edwin G.; Arias, Hugo R.; Damaj, M. Imad

Citation Style Language JSON

{
  "DOI": "10.1213/ANE.0000000000000902", 
  "abstract": "BACKGROUND: Positive allosteric modulators (PAMs) facilitate endogenous neurotransmission and/or enhance the efficacy of agonists without directly acting on the orthosteric binding sites. In this regard, selective 7 nicotinic acetylcholine receptor type II PAMs display antinociceptive activity in rodent chronic inflammatory and neuropathic pain models. This study investigates whether 3-furan-2-yl-N-p-tolyl-acrylamide (PAM-2), a new putative 7-selective type II PAM, attenuates experimental inflammatory and neuropathic pains in mice.", 
  "author": [
    {
      "family": "Bagdas", 
      "given": " Deniz"
    }, 
    {
      "family": "Targowska-Duda", 
      "given": " Katarzyna M."
    }, 
    {
      "family": "Lopez", 
      "given": " Jhon J."
    }, 
    {
      "family": "Perez", 
      "given": " Edwin G."
    }, 
    {
      "family": "Arias", 
      "given": " Hugo R."
    }, 
    {
      "family": "Damaj", 
      "given": " M. Imad"
    }
  ], 
  "container_title": "ANESTHESIA AND ANALGESIA", 
  "id": "78255", 
  "issue": "5", 
  "issued": {
    "date-parts": [
      [
        2015, 
        1, 
        1
      ]
    ]
  }, 
  "page": "1369-1377", 
  "title": "The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of alpha 7 Nicotinic Acetylcholine Receptors in Mice", 
  "type": "article-journal", 
  "volume": "121"
}