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Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors

Kilic, Burcu; Erdogan, Merve; Gulcan, Hayrettin O.; Aksakarl, Fatma; Oruklu, Nihan; Bagriacik, Emin U.; Dogruer, Deniz S.


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  <dc:creator>Kilic, Burcu</dc:creator>
  <dc:creator>Erdogan, Merve</dc:creator>
  <dc:creator>Gulcan, Hayrettin O.</dc:creator>
  <dc:creator>Aksakarl, Fatma</dc:creator>
  <dc:creator>Oruklu, Nihan</dc:creator>
  <dc:creator>Bagriacik, Emin U.</dc:creator>
  <dc:creator>Dogruer, Deniz S.</dc:creator>
  <dc:date>2019-01-01</dc:date>
  <dc:description>Background: With respect to the increase in the average life expectancy, Alzheimer Disease (AD), the most common form of age-related dementia, has become a major threat to the population over the age of 65 during the past several decades. The majority of AD treatments are focused on cholinergic and amyloid hypotheses.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/72229</dc:identifier>
  <dc:identifier>oai:zenodo.org:72229</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>MEDICINAL CHEMISTRY 15(1) 59-76</dc:source>
  <dc:title>Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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