1 Ocak 2019 Dergi makalesi Açık Erişim

Kilic, Burcu; Erdogan, Merve; Gulcan, Hayrettin O.; Aksakarl, Fatma; Oruklu, Nihan; Bagriacik, Emin U.; Dogruer, Deniz S.

Citation Style Language JSON

{
  "DOI": "10.2174/1573406414666180524073241", 
  "abstract": "Background: With respect to the increase in the average life expectancy, Alzheimer Disease (AD), the most common form of age-related dementia, has become a major threat to the population over the age of 65 during the past several decades. The majority of AD treatments are focused on cholinergic and amyloid hypotheses.", 
  "author": [
    {
      "family": "Kilic", 
      "given": " Burcu"
    }, 
    {
      "family": "Erdogan", 
      "given": " Merve"
    }, 
    {
      "family": "Gulcan", 
      "given": " Hayrettin O."
    }, 
    {
      "family": "Aksakarl", 
      "given": " Fatma"
    }, 
    {
      "family": "Oruklu", 
      "given": " Nihan"
    }, 
    {
      "family": "Bagriacik", 
      "given": " Emin U."
    }, 
    {
      "family": "Dogruer", 
      "given": " Deniz S."
    }
  ], 
  "container_title": "MEDICINAL CHEMISTRY", 
  "id": "72229", 
  "issue": "1", 
  "issued": {
    "date-parts": [
      [
        2019, 
        1, 
        1
      ]
    ]
  }, 
  "page": "59-76", 
  "title": "Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors", 
  "type": "article-journal", 
  "volume": "15"
}