Dergi makalesi Açık Erişim

Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors

Kilic, Burcu; Erdogan, Merve; Gulcan, Hayrettin O.; Aksakarl, Fatma; Oruklu, Nihan; Bagriacik, Emin U.; Dogruer, Deniz S.


JSON

{
  "conceptrecid": "72228", 
  "created": "2021-03-16T03:40:19.777148+00:00", 
  "doi": "10.2174/1573406414666180524073241", 
  "files": [
    {
      "bucket": "280f05ad-4115-4b66-baaf-39476a00c4ce", 
      "checksum": "md5:6837e8e9099e08d16d8a4f565dc3ff8c", 
      "key": "bib-c57ca51f-872c-4b59-9992-2529dafb7a5d.txt", 
      "links": {
        "self": "https://aperta.ulakbim.gov.tr/api/files/280f05ad-4115-4b66-baaf-39476a00c4ce/bib-c57ca51f-872c-4b59-9992-2529dafb7a5d.txt"
      }, 
      "size": 279, 
      "type": "txt"
    }
  ], 
  "id": 72229, 
  "links": {
    "badge": "https://aperta.ulakbim.gov.tr/badge/doi/10.2174/1573406414666180524073241.svg", 
    "bucket": "https://aperta.ulakbim.gov.tr/api/files/280f05ad-4115-4b66-baaf-39476a00c4ce", 
    "doi": "https://doi.org/10.2174/1573406414666180524073241", 
    "html": "https://aperta.ulakbim.gov.tr/record/72229", 
    "latest": "https://aperta.ulakbim.gov.tr/api/records/72229", 
    "latest_html": "https://aperta.ulakbim.gov.tr/record/72229"
  }, 
  "metadata": {
    "access_right": "open", 
    "access_right_category": "success", 
    "communities": [
      {
        "id": "tubitak-destekli-proje-yayinlari"
      }
    ], 
    "creators": [
      {
        "affiliation": "Gazi Univ, Fac Pharm, Dept Pharmaceut Chem, Ankara, Turkey", 
        "name": "Kilic, Burcu"
      }, 
      {
        "affiliation": "Gazi Univ, Fac Pharm, Dept Pharmaceut Chem, Ankara, Turkey", 
        "name": "Erdogan, Merve"
      }, 
      {
        "affiliation": "Eastern Mediterranean Univ, Fac Pharm, Dept Pharmaceut Chem, Gazimagosa, North Cyprus, Turkey", 
        "name": "Gulcan, Hayrettin O."
      }, 
      {
        "affiliation": "Hacettepe Univ, Dept Chem, Ankara, Turkey", 
        "name": "Aksakarl, Fatma"
      }, 
      {
        "affiliation": "Gazi Univ, Fac Med, Dept Immunol, Ankara, Turkey", 
        "name": "Oruklu, Nihan"
      }, 
      {
        "affiliation": "Gazi Univ, Fac Med, Dept Immunol, Ankara, Turkey", 
        "name": "Bagriacik, Emin U."
      }, 
      {
        "affiliation": "Gazi Univ, Fac Pharm, Dept Pharmaceut Chem, Ankara, Turkey", 
        "name": "Dogruer, Deniz S."
      }
    ], 
    "description": "Background: With respect to the increase in the average life expectancy, Alzheimer Disease (AD), the most common form of age-related dementia, has become a major threat to the population over the age of 65 during the past several decades. The majority of AD treatments are focused on cholinergic and amyloid hypotheses.", 
    "doi": "10.2174/1573406414666180524073241", 
    "has_grant": false, 
    "journal": {
      "issue": "1", 
      "pages": "59-76", 
      "title": "MEDICINAL CHEMISTRY", 
      "volume": "15"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2019-01-01", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "72229"
          }, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "72228"
          }
        }
      ]
    }, 
    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
    }, 
    "title": "Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors"
  }, 
  "owners": [
    1
  ], 
  "revision": 1, 
  "stats": {
    "downloads": 8.0, 
    "unique_downloads": 8.0, 
    "unique_views": 34.0, 
    "version_downloads": 8.0, 
    "version_unique_downloads": 8.0, 
    "version_unique_views": 34.0, 
    "version_views": 35.0, 
    "version_volume": 2232.0, 
    "views": 35.0, 
    "volume": 2232.0
  }, 
  "updated": "2021-03-16T03:40:19.834834+00:00"
}
35
8
görüntülenme
indirilme
Görüntülenme 35
İndirme 8
Veri hacmi 2.2 kB
Tekil görüntülenme 34
Tekil indirme 8

Alıntı yap