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L-proline derivatives based on a calix[4]arene scaffold as chiral organocatalysts for the direct asymmetric aldol reaction in water

Aktas, Mehmet; Uyanik, Arzu; Eymur, Serkan; Yilmaz, Mustafa


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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Aktas, Mehmet</dc:creator>
  <dc:creator>Uyanik, Arzu</dc:creator>
  <dc:creator>Eymur, Serkan</dc:creator>
  <dc:creator>Yilmaz, Mustafa</dc:creator>
  <dc:date>2016-01-01</dc:date>
  <dc:description>A new series of water-compatible proline catalysts (4-6) derived from calixarene bearing a hydrophobic nature have been synthesised. It was found that the compound 4 was a highly efficient organocatalyst for aldol reactions occurred in the water. Under optimised reaction conditions, high yields (up to 82%), good enantioselectivities (ee up to 81%) and high diastereoselectivities (dr up to 91:9) were obtained.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/58845</dc:identifier>
  <dc:identifier>oai:zenodo.org:58845</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>SUPRAMOLECULAR CHEMISTRY 28(5-6) 351-359</dc:source>
  <dc:title>L-proline derivatives based on a calix[4]arene scaffold as chiral organocatalysts for the direct asymmetric aldol reaction in water</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
</oai_dc:dc>
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