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L-proline derivatives based on a calix[4]arene scaffold as chiral organocatalysts for the direct asymmetric aldol reaction in water

Aktas, Mehmet; Uyanik, Arzu; Eymur, Serkan; Yilmaz, Mustafa


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{
  "DOI": "10.1080/10610278.2015.1073288", 
  "abstract": "A new series of water-compatible proline catalysts (4-6) derived from calixarene bearing a hydrophobic nature have been synthesised. It was found that the compound 4 was a highly efficient organocatalyst for aldol reactions occurred in the water. Under optimised reaction conditions, high yields (up to 82%), good enantioselectivities (ee up to 81%) and high diastereoselectivities (dr up to 91:9) were obtained.", 
  "author": [
    {
      "family": "Aktas", 
      "given": " Mehmet"
    }, 
    {
      "family": "Uyanik", 
      "given": " Arzu"
    }, 
    {
      "family": "Eymur", 
      "given": " Serkan"
    }, 
    {
      "family": "Yilmaz", 
      "given": " Mustafa"
    }
  ], 
  "container_title": "SUPRAMOLECULAR CHEMISTRY", 
  "id": "58845", 
  "issue": "5-6", 
  "issued": {
    "date-parts": [
      [
        2016, 
        1, 
        1
      ]
    ]
  }, 
  "page": "351-359", 
  "title": "L-proline derivatives based on a calix[4]arene scaffold as chiral organocatalysts for the direct asymmetric aldol reaction in water", 
  "type": "article-journal", 
  "volume": "28"
}
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