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gamma-Carboline AC190 analogues via palladium catalysed allene insertion stereo and regioselective 3-and 5-component cascades

Dondas, H. Ali; Hempshall, Aiden; Narramore, Sarah; Kilner, Colin; Fishwick, Colin W. G.; Grigg, Ronald


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  <dc:creator>Dondas, H. Ali</dc:creator>
  <dc:creator>Hempshall, Aiden</dc:creator>
  <dc:creator>Narramore, Sarah</dc:creator>
  <dc:creator>Kilner, Colin</dc:creator>
  <dc:creator>Fishwick, Colin W. G.</dc:creator>
  <dc:creator>Grigg, Ronald</dc:creator>
  <dc:date>2016-01-01</dc:date>
  <dc:description>gamma-Carbolines were prepared from pyrido[4,3-b]-5H-indoles via Pd(0)-catalysed, stereo and regioselective allene/uridine allene insertion 3- and 5-component cascades. This versatile reaction sequence gives a range of structurally diverse carboline derivatives and tolerates a broad range of substrates. The power of this approach has been harnessed to produce gamma-carboline based HDAC inhibitors. (C) 2016 Elsevier Ltd. All rights reserved.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/57931</dc:identifier>
  <dc:identifier>oai:zenodo.org:57931</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>TETRAHEDRON 72(10) 1316-1329</dc:source>
  <dc:title>gamma-Carboline AC190 analogues via palladium catalysed allene insertion stereo and regioselective 3-and 5-component cascades</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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