1 Ocak 2017 Dergi makalesi Açık Erişim

Alpugan, Serkan; Topkaya, Derya; Dumoulin, Fabienne

Citation Style Language JSON

{
  "DOI": "10.1142/S1088424617500961", 
  "abstract": "The tumor micro-environment is rich in glutathione. To exploit this feature for tumor-activatable porphyrin-based photosensitizers, a dimeric disulfide-bridged porphyrin has been designed and prepared, together with two reference derivatives, a non-cleavable dimer and a monomer. The three compounds have been investigated from a photochemical and photophysical point of view. It appears that the disulfide-bridged derivative exhibited intramolecular aggregation, but to an insufficient extent to induce a satisfying self-quenching of its photoproperties. Unlike expected, the non-cleavable dimer behaved like the monomeric derivative, due to the superior flexibility of the alkyl bridge over the disulfide bridge.", 
  "author": [
    {
      "family": "Alpugan", 
      "given": " Serkan"
    }, 
    {
      "family": "Topkaya", 
      "given": " Derya"
    }, 
    {
      "family": "Dumoulin", 
      "given": " Fabienne"
    }
  ], 
  "container_title": "JOURNAL OF PORPHYRINS AND PHTHALOCYANINES", 
  "id": "52273", 
  "issue": "12", 
  "issued": {
    "date-parts": [
      [
        2017, 
        1, 
        1
      ]
    ]
  }, 
  "page": "918-924", 
  "title": "Disulfide-bridge dimeric porphyrin and their reference compounds for glutathione-based specific tumor-activation", 
  "type": "article-journal", 
  "volume": "21"
}