1 Ocak 2020 Dergi makalesi Açık Erişim

Algarawi, Maha; Erkol, Hakan; Luk, Alex; Ha, Seunghoon; Unlu, Mehmet B.; Gulsen, Gultekin; Nouizi, Farouk

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        "name": "Algarawi, Maha"
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        "affiliation": "Bogazici Univ, Dept Phys, Istanbul, Turkey", 
        "name": "Erkol, Hakan"
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      {
        "affiliation": "Univ Calif Irvine, Ctr Funct Oncoimaging, Irvine, CA 92697 USA", 
        "name": "Luk, Alex"
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      {
        "affiliation": "Philips Healthcare, Pewaukee, WI 53002 USA", 
        "name": "Ha, Seunghoon"
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      {
        "affiliation": "Bogazici Univ, Dept Phys, Istanbul, Turkey", 
        "name": "Unlu, Mehmet B."
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      {
        "name": "Gulsen, Gultekin"
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      {
        "name": "Nouizi, Farouk"
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    "description": "Photo-magnetic imaging (PMI) is an emerging optical imaging modality that showed great performance on providing absorption maps with high resolution and quantitative accuracy. As a multi-modality technology, PMI warms up the imaged object using a near infrared laser while temperature variation is measured using magnetic resonance imaging. By probing tissue at multiple wavelengths, concentration of the main tissue chromophores such as oxy-and deoxy-hemoglobin, lipid, and water are obtained then used to derive functional parameters such as total hemoglobin concentration and relative oxygen saturation. In this paper, we present a multi-wavelength PMI system that was custom-built to host five different laser wavelengths. After recovering the high-resolution absorption maps, a least-squared minimization process was used to resolve the different chromophore concentration. The performance of the system was experimentally tested on a phantom with two different dyes. Their concentrations were successfully assessed with high spatial resolution and average accuracy of nearly 80%. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement", 
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      "issue": "8", 
      "pages": "4244-4254", 
      "title": "BIOMEDICAL OPTICS EXPRESS", 
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    "title": "Resolving tissue chromophore concentration at MRI resolution using multi-wavelength photo-magnetic imaging"
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