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Algarawi, Maha; Erkol, Hakan; Luk, Alex; Ha, Seunghoon; Unlu, Mehmet B.; Gulsen, Gultekin; Nouizi, Farouk
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd"> <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/5149</identifier> <creators> <creator> <creatorName>Algarawi, Maha</creatorName> <givenName>Maha</givenName> <familyName>Algarawi</familyName> </creator> <creator> <creatorName>Erkol, Hakan</creatorName> <givenName>Hakan</givenName> <familyName>Erkol</familyName> <affiliation>Bogazici Univ, Dept Phys, Istanbul, Turkey</affiliation> </creator> <creator> <creatorName>Luk, Alex</creatorName> <givenName>Alex</givenName> <familyName>Luk</familyName> <affiliation>Univ Calif Irvine, Ctr Funct Oncoimaging, Irvine, CA 92697 USA</affiliation> </creator> <creator> <creatorName>Ha, Seunghoon</creatorName> <givenName>Seunghoon</givenName> <familyName>Ha</familyName> <affiliation>Philips Healthcare, Pewaukee, WI 53002 USA</affiliation> </creator> <creator> <creatorName>Unlu, Mehmet B.</creatorName> <givenName>Mehmet B.</givenName> <familyName>Unlu</familyName> <affiliation>Bogazici Univ, Dept Phys, Istanbul, Turkey</affiliation> </creator> <creator> <creatorName>Gulsen, Gultekin</creatorName> <givenName>Gultekin</givenName> <familyName>Gulsen</familyName> </creator> <creator> <creatorName>Nouizi, Farouk</creatorName> <givenName>Farouk</givenName> <familyName>Nouizi</familyName> </creator> </creators> <titles> <title>Resolving Tissue Chromophore Concentration At Mri Resolution Using Multi-Wavelength Photo-Magnetic Imaging</title> </titles> <publisher>Aperta</publisher> <publicationYear>2020</publicationYear> <dates> <date dateType="Issued">2020-01-01</date> </dates> <resourceType resourceTypeGeneral="Text">Journal article</resourceType> <alternateIdentifiers> <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/5149</alternateIdentifier> </alternateIdentifiers> <relatedIdentifiers> <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1364/BOE.397538</relatedIdentifier> </relatedIdentifiers> <rightsList> <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights> <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights> </rightsList> <descriptions> <description descriptionType="Abstract">Photo-magnetic imaging (PMI) is an emerging optical imaging modality that showed great performance on providing absorption maps with high resolution and quantitative accuracy. As a multi-modality technology, PMI warms up the imaged object using a near infrared laser while temperature variation is measured using magnetic resonance imaging. By probing tissue at multiple wavelengths, concentration of the main tissue chromophores such as oxy-and deoxy-hemoglobin, lipid, and water are obtained then used to derive functional parameters such as total hemoglobin concentration and relative oxygen saturation. In this paper, we present a multi-wavelength PMI system that was custom-built to host five different laser wavelengths. After recovering the high-resolution absorption maps, a least-squared minimization process was used to resolve the different chromophore concentration. The performance of the system was experimentally tested on a phantom with two different dyes. Their concentrations were successfully assessed with high spatial resolution and average accuracy of nearly 80%. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement</description> </descriptions> </resource>
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