1 Ocak 2020 Dergi makalesi Açık Erişim

Algarawi, Maha; Erkol, Hakan; Luk, Alex; Ha, Seunghoon; Unlu, Mehmet B.; Gulsen, Gultekin; Nouizi, Farouk

Citation Style Language JSON

{
  "DOI": "10.1364/BOE.397538", 
  "abstract": "Photo-magnetic imaging (PMI) is an emerging optical imaging modality that showed great performance on providing absorption maps with high resolution and quantitative accuracy. As a multi-modality technology, PMI warms up the imaged object using a near infrared laser while temperature variation is measured using magnetic resonance imaging. By probing tissue at multiple wavelengths, concentration of the main tissue chromophores such as oxy-and deoxy-hemoglobin, lipid, and water are obtained then used to derive functional parameters such as total hemoglobin concentration and relative oxygen saturation. In this paper, we present a multi-wavelength PMI system that was custom-built to host five different laser wavelengths. After recovering the high-resolution absorption maps, a least-squared minimization process was used to resolve the different chromophore concentration. The performance of the system was experimentally tested on a phantom with two different dyes. Their concentrations were successfully assessed with high spatial resolution and average accuracy of nearly 80%. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement", 
  "author": [
    {
      "family": "Algarawi", 
      "given": " Maha"
    }, 
    {
      "family": "Erkol", 
      "given": " Hakan"
    }, 
    {
      "family": "Luk", 
      "given": " Alex"
    }, 
    {
      "family": "Ha", 
      "given": " Seunghoon"
    }, 
    {
      "family": "Unlu", 
      "given": " Mehmet B."
    }, 
    {
      "family": "Gulsen", 
      "given": " Gultekin"
    }, 
    {
      "family": "Nouizi", 
      "given": " Farouk"
    }
  ], 
  "container_title": "BIOMEDICAL OPTICS EXPRESS", 
  "id": "5149", 
  "issue": "8", 
  "issued": {
    "date-parts": [
      [
        2020, 
        1, 
        1
      ]
    ]
  }, 
  "page": "4244-4254", 
  "title": "Resolving tissue chromophore concentration at MRI resolution using multi-wavelength photo-magnetic imaging", 
  "type": "article-journal", 
  "volume": "11"
}