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Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone

Kurbanoglu, Esabi B.; Zilbeyaz, Kani; Kurbanoglu, Namudar I.; Taskin, Mesut; Kilic, Hamdullah


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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Kurbanoglu, Esabi B.</dc:creator>
  <dc:creator>Zilbeyaz, Kani</dc:creator>
  <dc:creator>Kurbanoglu, Namudar I.</dc:creator>
  <dc:creator>Taskin, Mesut</dc:creator>
  <dc:creator>Kilic, Hamdullah</dc:creator>
  <dc:date>2008-01-01</dc:date>
  <dc:description>The bioreduction of 1-acetonaphthone 1 by locally isolated Rhodotorula glutinis strains using ram horn peptone (RHP) gave (S)-(-)-1-(1'-naphthyl) ethanol ( 2), an important pharmaceutical intermediate. R. glutinis strains were isolated from the water of fermented Salix leaves. Optimum fermentation conditions for the production of 2 were 200 rpm, 32 degrees C, and pH 6.5. The production of 2 with excellent enantiomeric excess (&gt; 99%), and good conversion (100%) and yield (78%) under optimum conditions was achieved up to preparative scale via a fermenter. Wide temperature, pH, time, and agitation ranges did not affect the enantiomeric excess (ee) of the bioreduction product. A simple process for the isolation of R. glutinis was also developed.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/39797</dc:identifier>
  <dc:identifier>oai:zenodo.org:39797</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>TURKISH JOURNAL OF CHEMISTRY 32(6) 685-692</dc:source>
  <dc:title>Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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