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Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone

Kurbanoglu, Esabi B.; Zilbeyaz, Kani; Kurbanoglu, Namudar I.; Taskin, Mesut; Kilic, Hamdullah


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{
  "@context": "https://schema.org/", 
  "@id": 39797, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Arts & Sci, Dept Biol, TR-25240 Erzurum, Turkey", 
      "name": "Kurbanoglu, Esabi B."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Arts & Sci, Dept Chem, TR-25240 Erzurum, Turkey", 
      "name": "Zilbeyaz, Kani"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Sakarya Univ, Hendek Fac Educ, Dept Chem, TR-54300 Sakarya, Turkey", 
      "name": "Kurbanoglu, Namudar I."
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Arts & Sci, Dept Biol, TR-25240 Erzurum, Turkey", 
      "name": "Taskin, Mesut"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ataturk Univ, Fac Arts & Sci, Dept Chem, TR-25240 Erzurum, Turkey", 
      "name": "Kilic, Hamdullah"
    }
  ], 
  "datePublished": "2008-01-01", 
  "description": "The bioreduction of 1-acetonaphthone 1 by locally isolated Rhodotorula glutinis strains using ram horn peptone (RHP) gave (S)-(-)-1-(1'-naphthyl) ethanol ( 2), an important pharmaceutical intermediate. R. glutinis strains were isolated from the water of fermented Salix leaves. Optimum fermentation conditions for the production of 2 were 200 rpm, 32 degrees C, and pH 6.5. The production of 2 with excellent enantiomeric excess (> 99%), and good conversion (100%) and yield (78%) under optimum conditions was achieved up to preparative scale via a fermenter. Wide temperature, pH, time, and agitation ranges did not affect the enantiomeric excess (ee) of the bioreduction product. A simple process for the isolation of R. glutinis was also developed.", 
  "headline": "Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone", 
  "identifier": 39797, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone", 
  "url": "https://aperta.ulakbim.gov.tr/record/39797"
}
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