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Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone

Kurbanoglu, Esabi B.; Zilbeyaz, Kani; Kurbanoglu, Namudar I.; Taskin, Mesut; Kilic, Hamdullah


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/39797</identifier>
  <creators>
    <creator>
      <creatorName>Kurbanoglu, Esabi B.</creatorName>
      <givenName>Esabi B.</givenName>
      <familyName>Kurbanoglu</familyName>
      <affiliation>Ataturk Univ, Fac Arts &amp; Sci, Dept Biol, TR-25240 Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Zilbeyaz, Kani</creatorName>
      <givenName>Kani</givenName>
      <familyName>Zilbeyaz</familyName>
      <affiliation>Ataturk Univ, Fac Arts &amp; Sci, Dept Chem, TR-25240 Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kurbanoglu, Namudar I.</creatorName>
      <givenName>Namudar I.</givenName>
      <familyName>Kurbanoglu</familyName>
      <affiliation>Sakarya Univ, Hendek Fac Educ, Dept Chem, TR-54300 Sakarya, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Taskin, Mesut</creatorName>
      <givenName>Mesut</givenName>
      <familyName>Taskin</familyName>
      <affiliation>Ataturk Univ, Fac Arts &amp; Sci, Dept Biol, TR-25240 Erzurum, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kilic, Hamdullah</creatorName>
      <givenName>Hamdullah</givenName>
      <familyName>Kilic</familyName>
      <affiliation>Ataturk Univ, Fac Arts &amp; Sci, Dept Chem, TR-25240 Erzurum, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Production Of (S)-(-)-1-(1'-Napthyl) Ethanol By Rhodotorula Glutinis Isolate Using Ram Horn Peptone</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2008</publicationYear>
  <dates>
    <date dateType="Issued">2008-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/39797</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.81043/aperta.39796</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.81043/aperta.39797</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The bioreduction of 1-acetonaphthone 1 by locally isolated Rhodotorula glutinis strains using ram horn peptone (RHP) gave (S)-(-)-1-(1'-naphthyl) ethanol ( 2), an important pharmaceutical intermediate. R. glutinis strains were isolated from the water of fermented Salix leaves. Optimum fermentation conditions for the production of 2 were 200 rpm, 32 degrees C, and pH 6.5. The production of 2 with excellent enantiomeric excess (&amp;gt; 99%), and good conversion (100%) and yield (78%) under optimum conditions was achieved up to preparative scale via a fermenter. Wide temperature, pH, time, and agitation ranges did not affect the enantiomeric excess (ee) of the bioreduction product. A simple process for the isolation of R. glutinis was also developed.</description>
  </descriptions>
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