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Kurbanoglu, Esabi B.; Zilbeyaz, Kani; Kurbanoglu, Namudar I.; Taskin, Mesut; Kilic, Hamdullah
{ "URL": "https://aperta.ulakbim.gov.tr/record/39797", "abstract": "The bioreduction of 1-acetonaphthone 1 by locally isolated Rhodotorula glutinis strains using ram horn peptone (RHP) gave (S)-(-)-1-(1'-naphthyl) ethanol ( 2), an important pharmaceutical intermediate. R. glutinis strains were isolated from the water of fermented Salix leaves. Optimum fermentation conditions for the production of 2 were 200 rpm, 32 degrees C, and pH 6.5. The production of 2 with excellent enantiomeric excess (> 99%), and good conversion (100%) and yield (78%) under optimum conditions was achieved up to preparative scale via a fermenter. Wide temperature, pH, time, and agitation ranges did not affect the enantiomeric excess (ee) of the bioreduction product. A simple process for the isolation of R. glutinis was also developed.", "author": [ { "family": "Kurbanoglu", "given": " Esabi B." }, { "family": "Zilbeyaz", "given": " Kani" }, { "family": "Kurbanoglu", "given": " Namudar I." }, { "family": "Taskin", "given": " Mesut" }, { "family": "Kilic", "given": " Hamdullah" } ], "container_title": "TURKISH JOURNAL OF CHEMISTRY", "id": "39797", "issue": "6", "issued": { "date-parts": [ [ 2008, 1, 1 ] ] }, "page": "685-692", "title": "Production of (S)-(-)-1-(1'-Napthyl) Ethanol by Rhodotorula glutinis Isolate Using Ram Horn Peptone", "type": "article-journal", "volume": "32" }
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