1 Ocak 2018 Dergi makalesi Açık Erişim

Armutcu, Canan; Uzun, Lokman; Denizli, Adil

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  "@id": 33061, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Chem, Ankara, Turkey", 
      "name": "Armutcu, Canan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Chem, Ankara, Turkey", 
      "name": "Uzun, Lokman"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Hacettepe Univ, Dept Chem, Ankara, Turkey", 
      "name": "Denizli, Adil"
    }
  ], 
  "datePublished": "2018-01-01", 
  "description": "Automated on-line two-dimensional high-performance liquid chromatography method (2D-HPLC) is proposed to determine Ochratoxin A (OTA) in food samples as an alternative to OTA immunoaffinity column (IAC). An on-line 2D-HPLC system is designed for the analysis of OTA using an affinity-based monolithic column in the first dimension and reversed-phase C18 column in the second dimension. Initially, optimal OTA separation efficiency is determined through traditional HPLC system consisting of a P(HEMAPA) monolithic column coupled with HPLC system. Secondly, after providing optimum conditions, OTA determination was investigated through the 2D-HPLC system. According to results, 2D-HPLC system showed good linearity in the range 0.5 to 20 ng/mL with limit of detection (LOD) and limit of quantification (LOQ) values of 21.2 pg/mL and 64.3 pg/mL, respectively. The P(HEMAPA)-4 monolithic column displayed good recovery of OTA ranging from 104.34% to 107.33%. Relative standard deviations (RSD) varied in the range 0.21% to 1.31% thus indicating the efficiency of P(HEMAPA)-4 monolithic column developed for OTA. (C) 2018 Elsevier B.V. All rights reserved.", 
  "headline": "Determination of Ochratoxin A traces in foodstuffs: Comparison of an automated on-line two-dimensional high-performance liquid chromatography and off-line immunoaffinity-high-performance liquid chromatography system", 
  "identifier": 33061, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Determination of Ochratoxin A traces in foodstuffs: Comparison of an automated on-line two-dimensional high-performance liquid chromatography and off-line immunoaffinity-high-performance liquid chromatography system", 
  "url": "https://aperta.ulakbim.gov.tr/record/33061"
}