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Chemoenzymatic Conversion of Linoleic Acid into Conjugated Linoleic Acid

Demir, Ayhan S.; Talpur, Farah N.


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/28173</identifier>
  <creators>
    <creator>
      <creatorName>Demir, Ayhan S.</creatorName>
      <givenName>Ayhan S.</givenName>
      <familyName>Demir</familyName>
      <affiliation>Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Talpur, Farah N.</creatorName>
      <givenName>Farah N.</givenName>
      <familyName>Talpur</familyName>
    </creator>
  </creators>
  <titles>
    <title>Chemoenzymatic Conversion Of Linoleic Acid Into Conjugated Linoleic Acid</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2010</publicationYear>
  <dates>
    <date dateType="Issued">2010-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/28173</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1021/jf903521b</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">An efficient chemoenzymatic method for preparing conjugated linoleic acid (CLA) using free linoleic acid (LA) as a substrate is described. In the first step, LA was transformed into 10-hydroxy-cis-12-octadecenoic acid (HA) by the whole cells of Lactobacillus plantarum after 48 h of incubation. The preincubation of whole cells with 0.03% LA resulted in a better yield of HA (480 mg/g) compared to cells grown without LA. In a second fast microwave step, HA was converted to cis-9, trans-11-octadecadienoic acid in the presence of iodine as a catalyst over a silica gel surface. The advantage of this method in preparing cis-9,trans-11 CLA is simple via the whole cell bioconversion of LA into HA via L. plantarum followed by the fast microwave-assisted synthesis of cis-9,trans-11 CLA in higher yields.</description>
  </descriptions>
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