Veri seti Açık Erişim
Erdoğan, Metin; Çinkaya, Samet; Brenig, Bertram; Çelikeloğlu, Koray; Demirtaş, Mustafa; Sarıibrahimoğlu, Suat; Tekerli, Mustafa
<?xml version='1.0' encoding='UTF-8'?> <record xmlns="http://www.loc.gov/MARC21/slim"> <leader>00000nmm##2200000uu#4500</leader> <datafield tag="245" ind1=" " ind2=" "> <subfield code="a">Genome-wide Association Studies for Milk Production Traits and Persistency of First Calving Holstein Cattle in Türkiye</subfield> </datafield> <datafield tag="909" ind1="C" ind2="4"> <subfield code="p">Frontiers in Veterinary Science</subfield> </datafield> <controlfield tag="001">274008</controlfield> <datafield tag="520" ind1=" " ind2=" "> <subfield code="a"><p>The study presents a comprehensive investigation into the genetic determinants<br> of 100-day milk yield (100DMY), 305-day milk yield (305DMY), total milk yield<br> (TMY), and persistency using first lactation records of 374 Holstein heifers reared<br> in a private farm at &Ccedil;anakkale province of T&uuml;rkiye, employing a genome-wide<br> association study (GWAS) approach. The research underscores the substantial<br> genetic component underlying these economically important traits through<br> detailed descriptive statistics and heritability estimations. The estimated<br> moderate to high heritabilities (0.32&ndash;0.54) for milk production traits suggest the<br> feasibility of targeted genetic improvement strategies. By leveraging GWAS, the<br> study identifies many significant and suggestively significant single nucleotide<br> polymorphisms (SNP) associated with studied traits. Noteworthy genes have<br> identified in this analysis include BCAS3, MALRD1, CTNND2, DOCK1, TMEM132C,<br> NRP1, CNTNAP2, GPRIN2, PLEKHA5, GLRA1, SCN7A, HHEX, KTM2C, RAB40C,<br> RAB11FIP3, and FXYD6. These findings provide valuable understandings of<br> the genetic background of milk production and persistency in Holstein cattle,<br> shedding light on specific genomic regions and candidate genes playing pivotal<br> roles in these traits. This research contributes valuable knowledge to the field<br> of dairy cattle genetics and informs future breeding efforts to improve milk<br> production sustainability and efficiency in Holstein cattle populations.</p></subfield> </datafield> <datafield tag="650" ind1="1" ind2="7"> <subfield code="2">opendefinition.org</subfield> <subfield code="a">cc-by</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="0">(orcid)0000-0003-0736-4571</subfield> <subfield code="u">Afyon Kocatepe Üniversitesi</subfield> <subfield code="a">Çinkaya, Samet</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Institute of Veterinary Medicine, Georg August University Göttingen, Göttingen, Germany</subfield> <subfield code="a">Brenig, Bertram</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Afyon Kocatepe Üniversitesi</subfield> <subfield code="a">Çelikeloğlu, Koray</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Afyon Kocatepe Üniversitesi</subfield> <subfield code="a">Demirtaş, Mustafa</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Kaanlar Agriculture and Livestock Farm</subfield> <subfield code="a">Sarıibrahimoğlu, Suat</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Afyon Kocatepe Üniversitesi</subfield> <subfield code="a">Tekerli, Mustafa</subfield> </datafield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">dataset</subfield> </datafield> <datafield tag="542" ind1=" " ind2=" "> <subfield code="l">open</subfield> </datafield> <datafield tag="100" ind1=" " ind2=" "> <subfield code="u">Afyon Kocatepe Üniversitesi</subfield> <subfield code="a">Erdoğan, Metin</subfield> </datafield> <datafield tag="653" ind1=" " ind2=" "> <subfield code="a">gwas</subfield> </datafield> <datafield tag="653" ind1=" " ind2=" "> <subfield code="a">candidate genes</subfield> </datafield> <datafield tag="653" ind1=" " ind2=" "> <subfield code="a">milk production</subfield> </datafield> <datafield tag="653" ind1=" " ind2=" "> <subfield code="a">persistency</subfield> </datafield> <datafield tag="653" ind1=" " ind2=" "> <subfield code="a">Holstein heifers</subfield> </datafield> <datafield tag="653" ind1=" " ind2=" "> <subfield code="a">cattle</subfield> </datafield> <datafield tag="260" ind1=" " ind2=" "> <subfield code="c">2024-09-02</subfield> </datafield> <controlfield tag="005">20241009153034.0</controlfield> <datafield tag="909" ind1="C" ind2="O"> <subfield code="o">oai:aperta.ulakbim.gov.tr:274008</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="z">md5:afc106c6b60e6f92ab897acd405eb59b</subfield> <subfield code="s">3113257</subfield> <subfield code="u">https://aperta.ulakbim.gov.trrecord/274008/files/GenotypingData_SNPAnnotations.xlsx</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="z">md5:9d19b372579f996200f0acc5d59ec702</subfield> <subfield code="s">54179116</subfield> <subfield code="u">https://aperta.ulakbim.gov.trrecord/274008/files/GenotypingData.xlsx</subfield> </datafield> <datafield tag="540" ind1=" " ind2=" "> <subfield code="u">https://creativecommons.org/licenses/by-nc/4.0/</subfield> <subfield code="a">Creative Commons Attribution-NonCommercial</subfield> </datafield> <datafield tag="024" ind1=" " ind2=" "> <subfield code="a">10.3389/fvets.2024.1461075</subfield> <subfield code="2">doi</subfield> </datafield> <datafield tag="041" ind1=" " ind2=" "> <subfield code="a">eng</subfield> </datafield> </record>
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