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Erdoğan, Metin; Çinkaya, Samet; Brenig, Bertram; Çelikeloğlu, Koray; Demirtaş, Mustafa; Sarıibrahimoğlu, Suat; Tekerli, Mustafa
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd"> <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/274008</identifier> <creators> <creator> <creatorName>Erdoğan, Metin</creatorName> <givenName>Metin</givenName> <familyName>Erdoğan</familyName> <affiliation>Afyon Kocatepe Üniversitesi</affiliation> </creator> <creator> <creatorName>Çinkaya, Samet</creatorName> <givenName>Samet</givenName> <familyName>Çinkaya</familyName> <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0003-0736-4571</nameIdentifier> <affiliation>Afyon Kocatepe Üniversitesi</affiliation> </creator> <creator> <creatorName>Brenig, Bertram</creatorName> <givenName>Bertram</givenName> <familyName>Brenig</familyName> <affiliation>Institute of Veterinary Medicine, Georg August University Göttingen, Göttingen, Germany</affiliation> </creator> <creator> <creatorName>Çelikeloğlu, Koray</creatorName> <givenName>Koray</givenName> <familyName>Çelikeloğlu</familyName> <affiliation>Afyon Kocatepe Üniversitesi</affiliation> </creator> <creator> <creatorName>Demirtaş, Mustafa</creatorName> <givenName>Mustafa</givenName> <familyName>Demirtaş</familyName> <affiliation>Afyon Kocatepe Üniversitesi</affiliation> </creator> <creator> <creatorName>Sarıibrahimoğlu, Suat</creatorName> <givenName>Suat</givenName> <familyName>Sarıibrahimoğlu</familyName> <affiliation>Kaanlar Agriculture and Livestock Farm</affiliation> </creator> <creator> <creatorName>Tekerli, Mustafa</creatorName> <givenName>Mustafa</givenName> <familyName>Tekerli</familyName> <affiliation>Afyon Kocatepe Üniversitesi</affiliation> </creator> </creators> <titles> <title>Genome-Wide Association Studies For Milk Production Traits And Persistency Of First Calving Holstein Cattle In Türkiye</title> </titles> <publisher>Aperta</publisher> <publicationYear>2024</publicationYear> <subjects> <subject>gwas</subject> <subject>candidate genes</subject> <subject>milk production</subject> <subject>persistency</subject> <subject>Holstein heifers</subject> <subject>cattle</subject> </subjects> <dates> <date dateType="Issued">2024-09-02</date> </dates> <language>en</language> <resourceType resourceTypeGeneral="Dataset"/> <alternateIdentifiers> <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/274008</alternateIdentifier> </alternateIdentifiers> <relatedIdentifiers> <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.3389/fvets.2024.1461075</relatedIdentifier> </relatedIdentifiers> <rightsList> <rights rightsURI="https://creativecommons.org/licenses/by-nc/4.0/">Creative Commons Attribution-NonCommercial</rights> <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights> </rightsList> <descriptions> <description descriptionType="Abstract"><p>The study presents a comprehensive investigation into the genetic determinants<br> of 100-day milk yield (100DMY), 305-day milk yield (305DMY), total milk yield<br> (TMY), and persistency using first lactation records of 374 Holstein heifers reared<br> in a private farm at &Ccedil;anakkale province of T&uuml;rkiye, employing a genome-wide<br> association study (GWAS) approach. The research underscores the substantial<br> genetic component underlying these economically important traits through<br> detailed descriptive statistics and heritability estimations. The estimated<br> moderate to high heritabilities (0.32&ndash;0.54) for milk production traits suggest the<br> feasibility of targeted genetic improvement strategies. By leveraging GWAS, the<br> study identifies many significant and suggestively significant single nucleotide<br> polymorphisms (SNP) associated with studied traits. Noteworthy genes have<br> identified in this analysis include BCAS3, MALRD1, CTNND2, DOCK1, TMEM132C,<br> NRP1, CNTNAP2, GPRIN2, PLEKHA5, GLRA1, SCN7A, HHEX, KTM2C, RAB40C,<br> RAB11FIP3, and FXYD6. These findings provide valuable understandings of<br> the genetic background of milk production and persistency in Holstein cattle,<br> shedding light on specific genomic regions and candidate genes playing pivotal<br> roles in these traits. This research contributes valuable knowledge to the field<br> of dairy cattle genetics and informs future breeding efforts to improve milk<br> production sustainability and efficiency in Holstein cattle populations.</p></description> </descriptions> </resource>
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