2 Eylül 2024 Veri seti Açık Erişim

Erdoğan, Metin; Çinkaya, Samet; Brenig, Bertram; Çelikeloğlu, Koray; Demirtaş, Mustafa; Sarıibrahimoğlu, Suat; Tekerli, Mustafa

Citation Style Language JSON

{
  "DOI": "10.3389/fvets.2024.1461075", 
  "abstract": "<p>The study presents a comprehensive investigation into the genetic determinants<br>\nof 100-day milk yield (100DMY), 305-day milk yield (305DMY), total milk yield<br>\n(TMY), and persistency using first lactation records of 374 Holstein heifers reared<br>\nin a private farm at &Ccedil;anakkale province of T&uuml;rkiye, employing a genome-wide<br>\nassociation study (GWAS) approach. The research underscores the substantial<br>\ngenetic component underlying these economically important traits through<br>\ndetailed descriptive statistics and heritability estimations. The estimated<br>\nmoderate to high heritabilities (0.32&ndash;0.54) for milk production traits suggest the<br>\nfeasibility of targeted genetic improvement strategies. By leveraging GWAS, the<br>\nstudy identifies many significant and suggestively significant single nucleotide<br>\npolymorphisms (SNP) associated with studied traits. Noteworthy genes have<br>\nidentified in this analysis include BCAS3, MALRD1, CTNND2, DOCK1, TMEM132C,<br>\nNRP1, CNTNAP2, GPRIN2, PLEKHA5, GLRA1, SCN7A, HHEX, KTM2C, RAB40C,<br>\nRAB11FIP3, and FXYD6. These findings provide valuable understandings of<br>\nthe genetic background of milk production and persistency in Holstein cattle,<br>\nshedding light on specific genomic regions and candidate genes playing pivotal<br>\nroles in these traits. This research contributes valuable knowledge to the field<br>\nof dairy cattle genetics and informs future breeding efforts to improve milk<br>\nproduction sustainability and efficiency in Holstein cattle populations.</p>", 
  "author": [
    {
      "family": "Erdo\u011fan", 
      "given": " Metin"
    }, 
    {
      "family": "\u00c7inkaya", 
      "given": " Samet"
    }, 
    {
      "family": "Brenig", 
      "given": " Bertram"
    }, 
    {
      "family": "\u00c7elikelo\u011flu", 
      "given": " Koray"
    }, 
    {
      "family": "Demirta\u015f", 
      "given": " Mustafa"
    }, 
    {
      "family": "Sar\u0131ibrahimo\u011flu", 
      "given": " Suat"
    }, 
    {
      "family": "Tekerli", 
      "given": " Mustafa"
    }
  ], 
  "container_title": "Frontiers in Veterinary Science", 
  "id": "274008", 
  "issued": {
    "date-parts": [
      [
        2024, 
        9, 
        2
      ]
    ]
  }, 
  "language": "eng", 
  "title": "Genome-wide Association Studies for Milk Production Traits and Persistency of First Calving Holstein Cattle in T\u00fcrkiye", 
  "type": "dataset"
}