2 Eylül 2024 Veri seti Açık Erişim

Erdoğan, Metin; Çinkaya, Samet; Brenig, Bertram; Çelikeloğlu, Koray; Demirtaş, Mustafa; Sarıibrahimoğlu, Suat; Tekerli, Mustafa

JSON-LD (schema.org)

{
  "@context": "https://schema.org/", 
  "@id": "https://doi.org/10.3389/fvets.2024.1461075", 
  "@type": "Dataset", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
      "name": "Erdo\u011fan, Metin"
    }, 
    {
      "@id": "https://orcid.org/0000-0003-0736-4571", 
      "@type": "Person", 
      "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
      "name": "\u00c7inkaya, Samet"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Institute of Veterinary Medicine, Georg August University G\u00f6ttingen, G\u00f6ttingen, Germany", 
      "name": "Brenig, Bertram"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
      "name": "\u00c7elikelo\u011flu, Koray"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
      "name": "Demirta\u015f, Mustafa"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Kaanlar Agriculture and Livestock Farm", 
      "name": "Sar\u0131ibrahimo\u011flu, Suat"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
      "name": "Tekerli, Mustafa"
    }
  ], 
  "datePublished": "2024-09-02", 
  "description": "<p>The study presents a comprehensive investigation into the genetic determinants<br>\nof 100-day milk yield (100DMY), 305-day milk yield (305DMY), total milk yield<br>\n(TMY), and persistency using first lactation records of 374 Holstein heifers reared<br>\nin a private farm at &Ccedil;anakkale province of T&uuml;rkiye, employing a genome-wide<br>\nassociation study (GWAS) approach. The research underscores the substantial<br>\ngenetic component underlying these economically important traits through<br>\ndetailed descriptive statistics and heritability estimations. The estimated<br>\nmoderate to high heritabilities (0.32&ndash;0.54) for milk production traits suggest the<br>\nfeasibility of targeted genetic improvement strategies. By leveraging GWAS, the<br>\nstudy identifies many significant and suggestively significant single nucleotide<br>\npolymorphisms (SNP) associated with studied traits. Noteworthy genes have<br>\nidentified in this analysis include BCAS3, MALRD1, CTNND2, DOCK1, TMEM132C,<br>\nNRP1, CNTNAP2, GPRIN2, PLEKHA5, GLRA1, SCN7A, HHEX, KTM2C, RAB40C,<br>\nRAB11FIP3, and FXYD6. These findings provide valuable understandings of<br>\nthe genetic background of milk production and persistency in Holstein cattle,<br>\nshedding light on specific genomic regions and candidate genes playing pivotal<br>\nroles in these traits. This research contributes valuable knowledge to the field<br>\nof dairy cattle genetics and informs future breeding efforts to improve milk<br>\nproduction sustainability and efficiency in Holstein cattle populations.</p>", 
  "distribution": [
    {
      "@type": "DataDownload", 
      "contentUrl": "https://aperta.ulakbim.gov.tr/api/files/9f08746f-4253-41e9-afb2-4541e196f907/GenotypingData_SNPAnnotations.xlsx", 
      "fileFormat": "xlsx"
    }, 
    {
      "@type": "DataDownload", 
      "contentUrl": "https://aperta.ulakbim.gov.tr/api/files/9f08746f-4253-41e9-afb2-4541e196f907/GenotypingData.xlsx", 
      "fileFormat": "xlsx"
    }
  ], 
  "identifier": "https://doi.org/10.3389/fvets.2024.1461075", 
  "inLanguage": {
    "@type": "Language", 
    "alternateName": "eng", 
    "name": "English"
  }, 
  "keywords": [
    "gwas", 
    "candidate genes", 
    "milk production", 
    "persistency", 
    "Holstein heifers", 
    "cattle"
  ], 
  "license": "https://creativecommons.org/licenses/by-nc/4.0/", 
  "name": "Genome-wide Association Studies for Milk Production Traits and Persistency of First Calving Holstein Cattle in T\u00fcrkiye", 
  "url": "https://aperta.ulakbim.gov.tr/record/274008"
}