2 Eylül 2024 Veri seti Açık Erişim

Erdoğan, Metin; Çinkaya, Samet; Brenig, Bertram; Çelikeloğlu, Koray; Demirtaş, Mustafa; Sarıibrahimoğlu, Suat; Tekerli, Mustafa

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  "created": "2024-10-09T15:30:34.097388+00:00", 
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    "creators": [
      {
        "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
        "name": "Erdo\u011fan, Metin"
      }, 
      {
        "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
        "name": "\u00c7inkaya, Samet", 
        "orcid": "0000-0003-0736-4571"
      }, 
      {
        "affiliation": "Institute of Veterinary Medicine, Georg August University G\u00f6ttingen, G\u00f6ttingen, Germany", 
        "name": "Brenig, Bertram"
      }, 
      {
        "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
        "name": "\u00c7elikelo\u011flu, Koray"
      }, 
      {
        "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
        "name": "Demirta\u015f, Mustafa"
      }, 
      {
        "affiliation": "Kaanlar Agriculture and Livestock Farm", 
        "name": "Sar\u0131ibrahimo\u011flu, Suat"
      }, 
      {
        "affiliation": "Afyon Kocatepe \u00dcniversitesi", 
        "name": "Tekerli, Mustafa"
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    "description": "<p>The study presents a comprehensive investigation into the genetic determinants<br>\nof 100-day milk yield (100DMY), 305-day milk yield (305DMY), total milk yield<br>\n(TMY), and persistency using first lactation records of 374 Holstein heifers reared<br>\nin a private farm at &Ccedil;anakkale province of T&uuml;rkiye, employing a genome-wide<br>\nassociation study (GWAS) approach. The research underscores the substantial<br>\ngenetic component underlying these economically important traits through<br>\ndetailed descriptive statistics and heritability estimations. The estimated<br>\nmoderate to high heritabilities (0.32&ndash;0.54) for milk production traits suggest the<br>\nfeasibility of targeted genetic improvement strategies. By leveraging GWAS, the<br>\nstudy identifies many significant and suggestively significant single nucleotide<br>\npolymorphisms (SNP) associated with studied traits. Noteworthy genes have<br>\nidentified in this analysis include BCAS3, MALRD1, CTNND2, DOCK1, TMEM132C,<br>\nNRP1, CNTNAP2, GPRIN2, PLEKHA5, GLRA1, SCN7A, HHEX, KTM2C, RAB40C,<br>\nRAB11FIP3, and FXYD6. These findings provide valuable understandings of<br>\nthe genetic background of milk production and persistency in Holstein cattle,<br>\nshedding light on specific genomic regions and candidate genes playing pivotal<br>\nroles in these traits. This research contributes valuable knowledge to the field<br>\nof dairy cattle genetics and informs future breeding efforts to improve milk<br>\nproduction sustainability and efficiency in Holstein cattle populations.</p>", 
    "doi": "10.3389/fvets.2024.1461075", 
    "has_grant": false, 
    "journal": {
      "title": "Frontiers in Veterinary Science"
    }, 
    "keywords": [
      "gwas", 
      "candidate genes", 
      "milk production", 
      "persistency", 
      "Holstein heifers", 
      "cattle"
    ], 
    "language": "eng", 
    "license": {
      "id": "cc-by-nc-4.0"
    }, 
    "publication_date": "2024-09-02", 
    "relations": {
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    "resource_type": {
      "title": "Veri seti", 
      "type": "dataset"
    }, 
    "science_branches": [
      "Sa\u011fl\u0131k Bilimleri > Veteriner Bilimleri > Zootekni ve Hayvan Besleme > Zootekni (Yeti\u015ftirme ve Islah) > B\u00fcy\u00fckba\u015f"
    ], 
    "title": "Genome-wide Association Studies for Milk Production Traits and Persistency of First Calving Holstein Cattle in T\u00fcrkiye"
  }, 
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    2428
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