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The ovulatory response to human chorionic gonadotropin administration on day 4 post timed artificial insemination improved fertility in repeat breeder cows

Yilmazbas-Mecitoglu, Gulnaz; Gumen, Ahmet; Karakaya-Bilen, Ebru; Keskin, Abdulkadir; Guner, Baris; Cakircali, Rabia


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  <dc:creator>Yilmazbas-Mecitoglu, Gulnaz</dc:creator>
  <dc:creator>Gumen, Ahmet</dc:creator>
  <dc:creator>Karakaya-Bilen, Ebru</dc:creator>
  <dc:creator>Keskin, Abdulkadir</dc:creator>
  <dc:creator>Guner, Baris</dc:creator>
  <dc:creator>Cakircali, Rabia</dc:creator>
  <dc:date>2021-01-01</dc:date>
  <dc:description>This study focused on determining the success of inducing endogenous progesterone source (by formation of accessory corpus luteum) by human chorionic gonadotropin (hCG) administration on day 4 post timed artificial insemination (TAI) and on evaluating the effect of the day of hCG administration (day 4 or 5 post TAI) on pregnancy rates in repeat breeder cows according to their responses to hCG administrations. Non-pregnant cyclic lactating Holstein dairy cows with more than three services despite no clinical reproductive abnormalities were enrolled in the study. All cows (n = 192) received the Ovsynch protocol (GnRH-7d-PGF(2 alpha)-56h-GnRH-16/18h-TAI) and hCG administration (1500 IU, i.m.) was performed in group hCG4 (n = 64) on day 4 and in group hCG5 (n = 68) on day 5 post TAI. The control group (CON, n = 60) did not receive any hCG treatment. The responses (ovulation rate) to hCG (similar to 64%) were similar on days 4 and 5 post TAI. Pregnancy per AI (P/AI) at 31 days was similar among the groups (48.3% in CON, 48.4% in hCG4, and 42.6% in hCG5). Regardless of the day of the treatment (hCG4 + hCG5), the cows had an ovulatory response to hCG (54.1%), and a greater P/AI (P = 0.007) at 31 days than those without a response (29.8%). The administration of hCG on either day 4 or 5 post TAI did not increase overall pregnancy rates, however, the ovulatory response to the post TAI hCG administration on day 4 improved fertility in repeat breeder cows. Further studies are needed with a larger number of animals to reveal this potentiallly beneficial effect.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/234462</dc:identifier>
  <dc:identifier>oai:aperta.ulakbim.gov.tr:234462</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>ACTA VETERINARIA BRNO 90(1) 15-20</dc:source>
  <dc:title>The ovulatory response to human chorionic gonadotropin administration on day 4 post timed artificial insemination improved fertility in repeat breeder cows</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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