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The ovulatory response to human chorionic gonadotropin administration on day 4 post timed artificial insemination improved fertility in repeat breeder cows

Yilmazbas-Mecitoglu, Gulnaz; Gumen, Ahmet; Karakaya-Bilen, Ebru; Keskin, Abdulkadir; Guner, Baris; Cakircali, Rabia


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/234462</identifier>
  <creators>
    <creator>
      <creatorName>Yilmazbas-Mecitoglu, Gulnaz</creatorName>
      <givenName>Gulnaz</givenName>
      <familyName>Yilmazbas-Mecitoglu</familyName>
      <affiliation>Univ Bursa Uludag, Fac Vet Med, Dept Obstet &amp; Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Gumen, Ahmet</creatorName>
      <givenName>Ahmet</givenName>
      <familyName>Gumen</familyName>
      <affiliation>Univ Bursa Uludag, Fac Vet Med, Dept Obstet &amp; Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karakaya-Bilen, Ebru</creatorName>
      <givenName>Ebru</givenName>
      <familyName>Karakaya-Bilen</familyName>
      <affiliation>Univ Siirt, Fac Vet Med, Dept Obstet &amp; Gynecol, Siirt, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Keskin, Abdulkadir</creatorName>
      <givenName>Abdulkadir</givenName>
      <familyName>Keskin</familyName>
      <affiliation>Univ Bursa Uludag, Fac Vet Med, Dept Obstet &amp; Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Guner, Baris</creatorName>
      <givenName>Baris</givenName>
      <familyName>Guner</familyName>
      <affiliation>Univ Balikesir, Fac Vet Med, Dept Obstet &amp; Gynecol, Balikesir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Cakircali, Rabia</creatorName>
      <givenName>Rabia</givenName>
      <familyName>Cakircali</familyName>
      <affiliation>Univ Bursa Uludag, Fac Vet Med, Dept Obstet &amp; Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The Ovulatory Response To Human Chorionic Gonadotropin Administration On Day 4 Post Timed Artificial Insemination Improved Fertility In Repeat Breeder Cows</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/234462</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.2754/avb202190010015</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">This study focused on determining the success of inducing endogenous progesterone source (by formation of accessory corpus luteum) by human chorionic gonadotropin (hCG) administration on day 4 post timed artificial insemination (TAI) and on evaluating the effect of the day of hCG administration (day 4 or 5 post TAI) on pregnancy rates in repeat breeder cows according to their responses to hCG administrations. Non-pregnant cyclic lactating Holstein dairy cows with more than three services despite no clinical reproductive abnormalities were enrolled in the study. All cows (n = 192) received the Ovsynch protocol (GnRH-7d-PGF(2 alpha)-56h-GnRH-16/18h-TAI) and hCG administration (1500 IU, i.m.) was performed in group hCG4 (n = 64) on day 4 and in group hCG5 (n = 68) on day 5 post TAI. The control group (CON, n = 60) did not receive any hCG treatment. The responses (ovulation rate) to hCG (similar to 64%) were similar on days 4 and 5 post TAI. Pregnancy per AI (P/AI) at 31 days was similar among the groups (48.3% in CON, 48.4% in hCG4, and 42.6% in hCG5). Regardless of the day of the treatment (hCG4 + hCG5), the cows had an ovulatory response to hCG (54.1%), and a greater P/AI (P = 0.007) at 31 days than those without a response (29.8%). The administration of hCG on either day 4 or 5 post TAI did not increase overall pregnancy rates, however, the ovulatory response to the post TAI hCG administration on day 4 improved fertility in repeat breeder cows. Further studies are needed with a larger number of animals to reveal this potentiallly beneficial effect.</description>
  </descriptions>
</resource>
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