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The ovulatory response to human chorionic gonadotropin administration on day 4 post timed artificial insemination improved fertility in repeat breeder cows

Yilmazbas-Mecitoglu, Gulnaz; Gumen, Ahmet; Karakaya-Bilen, Ebru; Keskin, Abdulkadir; Guner, Baris; Cakircali, Rabia


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{
  "@context": "https://schema.org/", 
  "@id": 234462, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Univ Bursa Uludag, Fac Vet Med, Dept Obstet & Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey", 
      "name": "Yilmazbas-Mecitoglu, Gulnaz"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Bursa Uludag, Fac Vet Med, Dept Obstet & Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey", 
      "name": "Gumen, Ahmet"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Siirt, Fac Vet Med, Dept Obstet & Gynecol, Siirt, Turkey", 
      "name": "Karakaya-Bilen, Ebru"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Bursa Uludag, Fac Vet Med, Dept Obstet & Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey", 
      "name": "Keskin, Abdulkadir"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Balikesir, Fac Vet Med, Dept Obstet & Gynecol, Balikesir, Turkey", 
      "name": "Guner, Baris"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Bursa Uludag, Fac Vet Med, Dept Obstet & Gynecol, Gonilde Campus, TR-16059 Bursa, Turkey", 
      "name": "Cakircali, Rabia"
    }
  ], 
  "datePublished": "2021-01-01", 
  "description": "This study focused on determining the success of inducing endogenous progesterone source (by formation of accessory corpus luteum) by human chorionic gonadotropin (hCG) administration on day 4 post timed artificial insemination (TAI) and on evaluating the effect of the day of hCG administration (day 4 or 5 post TAI) on pregnancy rates in repeat breeder cows according to their responses to hCG administrations. Non-pregnant cyclic lactating Holstein dairy cows with more than three services despite no clinical reproductive abnormalities were enrolled in the study. All cows (n = 192) received the Ovsynch protocol (GnRH-7d-PGF(2 alpha)-56h-GnRH-16/18h-TAI) and hCG administration (1500 IU, i.m.) was performed in group hCG4 (n = 64) on day 4 and in group hCG5 (n = 68) on day 5 post TAI. The control group (CON, n = 60) did not receive any hCG treatment. The responses (ovulation rate) to hCG (similar to 64%) were similar on days 4 and 5 post TAI. Pregnancy per AI (P/AI) at 31 days was similar among the groups (48.3% in CON, 48.4% in hCG4, and 42.6% in hCG5). Regardless of the day of the treatment (hCG4 + hCG5), the cows had an ovulatory response to hCG (54.1%), and a greater P/AI (P = 0.007) at 31 days than those without a response (29.8%). The administration of hCG on either day 4 or 5 post TAI did not increase overall pregnancy rates, however, the ovulatory response to the post TAI hCG administration on day 4 improved fertility in repeat breeder cows. Further studies are needed with a larger number of animals to reveal this potentiallly beneficial effect.", 
  "headline": "The ovulatory response to human chorionic gonadotropin administration on day 4 post timed artificial insemination improved fertility in repeat breeder cows", 
  "identifier": 234462, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "The ovulatory response to human chorionic gonadotropin administration on day 4 post timed artificial insemination improved fertility in repeat breeder cows", 
  "url": "https://aperta.ulakbim.gov.tr/record/234462"
}
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