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ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart

Jost, N.; Nagy, N.; Corici, C.; Kohajda, Z.; Horvath, A.; Acsai, K.; Biliczki, P.; Levijoki, J.; Pollesello, P.; Koskelainen, T.; Otsomaa, L.; Toth, A.; Papp, J. Gy; Varro, A.; Virag, L.


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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Jost, N.</dc:creator>
  <dc:creator>Nagy, N.</dc:creator>
  <dc:creator>Corici, C.</dc:creator>
  <dc:creator>Kohajda, Z.</dc:creator>
  <dc:creator>Horvath, A.</dc:creator>
  <dc:creator>Acsai, K.</dc:creator>
  <dc:creator>Biliczki, P.</dc:creator>
  <dc:creator>Levijoki, J.</dc:creator>
  <dc:creator>Pollesello, P.</dc:creator>
  <dc:creator>Koskelainen, T.</dc:creator>
  <dc:creator>Otsomaa, L.</dc:creator>
  <dc:creator>Toth, A.</dc:creator>
  <dc:creator>Papp, J. Gy</dc:creator>
  <dc:creator>Varro, A.</dc:creator>
  <dc:creator>Virag, L.</dc:creator>
  <dc:date>2013-01-01</dc:date>
  <dc:description>Background and PurposeAt present there are no small molecule inhibitors that show strong selectivity for the Na+/Ca2+ exchanger (NCX). Hence, we studied the electrophysiological effects of acute administration of ORM-10103, a new NCX inhibitor, on the NCX and L-type Ca2+ currents and on the formation of early and delayed afterdepolarizations.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/14243</dc:identifier>
  <dc:identifier>oai:zenodo.org:14243</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>BRITISH JOURNAL OF PHARMACOLOGY 170(4) 768-778</dc:source>
  <dc:title>ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
</oai_dc:dc>
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