Dergi makalesi Açık Erişim
Kayce, Peyker; Kirmizigul, Suheyla
<?xml version='1.0' encoding='UTF-8'?> <record xmlns="http://www.loc.gov/MARC21/slim"> <leader>00000nam##2200000uu#4500</leader> <datafield tag="245" ind1=" " ind2=" "> <subfield code="a">Isolation and identification of a new saponin from Cephalaria aytachii</subfield> </datafield> <datafield tag="909" ind1="C" ind2="4"> <subfield code="p">NATURAL PRODUCT RESEARCH</subfield> <subfield code="v">31</subfield> <subfield code="n">1</subfield> <subfield code="c">50-57</subfield> </datafield> <controlfield tag="001">111110</controlfield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="520" ind1=" " ind2=" "> <subfield code="a">A new hederagenin-type triterpenoid glycoside (1) named Aytachoside A, along with eight known triterpene glycosides, were isolated from the aerial parts of Cephalaria aytachii Gokturk and Sumbul (Dipsacaceae). The structures of compounds 1-9 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical examinations. The antimicrobial effect of compound 1 was found considerably active against Escherichia coli, Pseudomonas aeruginosa and especially Salmonella typhimurium microorganisms using the MIC method. Although compound 1 was found not to have a remarkable toxic effect at a concentration lower than 300g/mL, cytotoxic activity tests demonstrated that prosapogenin 1a exhibits a significant cytotoxic activity against HeLa cell lines using the MTT assay for the first time.</subfield> </datafield> <datafield tag="650" ind1="1" ind2="7"> <subfield code="2">opendefinition.org</subfield> <subfield code="a">cc-by</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey</subfield> <subfield code="a">Kirmizigul, Suheyla</subfield> </datafield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="b">article</subfield> <subfield code="a">publication</subfield> </datafield> <datafield tag="542" ind1=" " ind2=" "> <subfield code="l">open</subfield> </datafield> <datafield tag="100" ind1=" " ind2=" "> <subfield code="u">Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey</subfield> <subfield code="a">Kayce, Peyker</subfield> </datafield> <datafield tag="260" ind1=" " ind2=" "> <subfield code="c">2017-01-01</subfield> </datafield> <controlfield tag="005">20210420141623.0</controlfield> <datafield tag="909" ind1="C" ind2="O"> <subfield code="o">oai:zenodo.org:111110</subfield> <subfield code="p">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="z">md5:53570e12372e896141f3c89a24570cf3</subfield> <subfield code="s">146</subfield> <subfield code="u">https://aperta.ulakbim.gov.trrecord/111110/files/bib-79c14352-3bb2-4b07-9315-663f90a9a430.txt</subfield> </datafield> <datafield tag="540" ind1=" " ind2=" "> <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield> <subfield code="a">Creative Commons Attribution</subfield> </datafield> <datafield tag="024" ind1=" " ind2=" "> <subfield code="a">10.1080/14786419.2016.1212029</subfield> <subfield code="2">doi</subfield> </datafield> </record>
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