1 Ocak 2017 Dergi makalesi Açık Erişim

Kayce, Peyker; Kirmizigul, Suheyla

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  "@id": 111110, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey", 
      "name": "Kayce, Peyker"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey", 
      "name": "Kirmizigul, Suheyla"
    }
  ], 
  "datePublished": "2017-01-01", 
  "description": "A new hederagenin-type triterpenoid glycoside (1) named Aytachoside A, along with eight known triterpene glycosides, were isolated from the aerial parts of Cephalaria aytachii Gokturk and Sumbul (Dipsacaceae). The structures of compounds 1-9 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical examinations. The antimicrobial effect of compound 1 was found considerably active against Escherichia coli, Pseudomonas aeruginosa and especially Salmonella typhimurium microorganisms using the MIC method. Although compound 1 was found not to have a remarkable toxic effect at a concentration lower than 300g/mL, cytotoxic activity tests demonstrated that prosapogenin 1a exhibits a significant cytotoxic activity against HeLa cell lines using the MTT assay for the first time.", 
  "headline": "Isolation and identification of a new saponin from Cephalaria aytachii", 
  "identifier": 111110, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Isolation and identification of a new saponin from Cephalaria aytachii", 
  "url": "https://aperta.ulakbim.gov.tr/record/111110"
}