1 Ocak 2017 Dergi makalesi Açık Erişim

Kayce, Peyker; Kirmizigul, Suheyla

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        "affiliation": "Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey", 
        "name": "Kayce, Peyker"
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        "affiliation": "Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey", 
        "name": "Kirmizigul, Suheyla"
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    "description": "A new hederagenin-type triterpenoid glycoside (1) named Aytachoside A, along with eight known triterpene glycosides, were isolated from the aerial parts of Cephalaria aytachii Gokturk and Sumbul (Dipsacaceae). The structures of compounds 1-9 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical examinations. The antimicrobial effect of compound 1 was found considerably active against Escherichia coli, Pseudomonas aeruginosa and especially Salmonella typhimurium microorganisms using the MIC method. Although compound 1 was found not to have a remarkable toxic effect at a concentration lower than 300g/mL, cytotoxic activity tests demonstrated that prosapogenin 1a exhibits a significant cytotoxic activity against HeLa cell lines using the MTT assay for the first time.", 
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      "issue": "1", 
      "pages": "50-57", 
      "title": "NATURAL PRODUCT RESEARCH", 
      "volume": "31"
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    "title": "Isolation and identification of a new saponin from Cephalaria aytachii"
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