1 Ocak 2017 Dergi makalesi Açık Erişim

Kayce, Peyker; Kirmizigul, Suheyla

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/111110</identifier>
  <creators>
    <creator>
      <creatorName>Kayce, Peyker</creatorName>
      <givenName>Peyker</givenName>
      <familyName>Kayce</familyName>
      <affiliation>Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kirmizigul, Suheyla</creatorName>
      <givenName>Suheyla</givenName>
      <familyName>Kirmizigul</familyName>
      <affiliation>Ege Univ, Dept Chem, Fac Sci, Izmir, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Isolation And Identification Of A New Saponin From Cephalaria Aytachii</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/111110</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1080/14786419.2016.1212029</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">A new hederagenin-type triterpenoid glycoside (1) named Aytachoside A, along with eight known triterpene glycosides, were isolated from the aerial parts of Cephalaria aytachii Gokturk and Sumbul (Dipsacaceae). The structures of compounds 1-9 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical examinations. The antimicrobial effect of compound 1 was found considerably active against Escherichia coli, Pseudomonas aeruginosa and especially Salmonella typhimurium microorganisms using the MIC method. Although compound 1 was found not to have a remarkable toxic effect at a concentration lower than 300g/mL, cytotoxic activity tests demonstrated that prosapogenin 1a exhibits a significant cytotoxic activity against HeLa cell lines using the MTT assay for the first time.</description>
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