Dergi makalesi Açık Erişim
Kayce, Peyker; Kirmizigul, Suheyla
{ "DOI": "10.1080/14786419.2016.1212029", "abstract": "A new hederagenin-type triterpenoid glycoside (1) named Aytachoside A, along with eight known triterpene glycosides, were isolated from the aerial parts of Cephalaria aytachii Gokturk and Sumbul (Dipsacaceae). The structures of compounds 1-9 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical examinations. The antimicrobial effect of compound 1 was found considerably active against Escherichia coli, Pseudomonas aeruginosa and especially Salmonella typhimurium microorganisms using the MIC method. Although compound 1 was found not to have a remarkable toxic effect at a concentration lower than 300g/mL, cytotoxic activity tests demonstrated that prosapogenin 1a exhibits a significant cytotoxic activity against HeLa cell lines using the MTT assay for the first time.", "author": [ { "family": "Kayce", "given": " Peyker" }, { "family": "Kirmizigul", "given": " Suheyla" } ], "container_title": "NATURAL PRODUCT RESEARCH", "id": "111110", "issue": "1", "issued": { "date-parts": [ [ 2017, 1, 1 ] ] }, "page": "50-57", "title": "Isolation and identification of a new saponin from Cephalaria aytachii", "type": "article-journal", "volume": "31" }
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