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Isolation and identification of a new saponin from Cephalaria aytachii

Kayce, Peyker; Kirmizigul, Suheyla


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{
  "DOI": "10.1080/14786419.2016.1212029", 
  "abstract": "A new hederagenin-type triterpenoid glycoside (1) named Aytachoside A, along with eight known triterpene glycosides, were isolated from the aerial parts of Cephalaria aytachii Gokturk and Sumbul (Dipsacaceae). The structures of compounds 1-9 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical examinations. The antimicrobial effect of compound 1 was found considerably active against Escherichia coli, Pseudomonas aeruginosa and especially Salmonella typhimurium microorganisms using the MIC method. Although compound 1 was found not to have a remarkable toxic effect at a concentration lower than 300g/mL, cytotoxic activity tests demonstrated that prosapogenin 1a exhibits a significant cytotoxic activity against HeLa cell lines using the MTT assay for the first time.", 
  "author": [
    {
      "family": "Kayce", 
      "given": " Peyker"
    }, 
    {
      "family": "Kirmizigul", 
      "given": " Suheyla"
    }
  ], 
  "container_title": "NATURAL PRODUCT RESEARCH", 
  "id": "111110", 
  "issue": "1", 
  "issued": {
    "date-parts": [
      [
        2017, 
        1, 
        1
      ]
    ]
  }, 
  "page": "50-57", 
  "title": "Isolation and identification of a new saponin from Cephalaria aytachii", 
  "type": "article-journal", 
  "volume": "31"
}
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