Dergi makalesi Açık Erişim
Safak, Serife; Vatan, Ozgur; Cinkilic, Nilufer; Karaca, Esra
{ "@context": "https://schema.org/", "@id": 9969, "@type": "ScholarlyArticle", "creator": [ { "@type": "Person", "affiliation": "Namik Kemal Univ, Corlu Fac Engn, Dept Text Engn, TR-59860 Corlu, Tekirdag, Turkey", "name": "Safak, Serife" }, { "@type": "Person", "affiliation": "Bursa Uludag Univ, Fac Arts & Sci, Dept Biol, TR-16059 Bursa, Turkey", "name": "Vatan, Ozgur" }, { "@type": "Person", "affiliation": "Bursa Uludag Univ, Fac Arts & Sci, Dept Biol, TR-16059 Bursa, Turkey", "name": "Cinkilic, Nilufer" }, { "@type": "Person", "affiliation": "Bursa Uludag Univ, Fac Engn, Dept Text Engn, TR-16059 Bursa, Turkey", "name": "Karaca, Esra" } ], "datePublished": "2020-01-01", "description": "Post-operative adhesions are one of the most important problems faced by patients and surgeons. In this study, nanofibrous mats were produced as novel surgical adhesion barrier from polysaccharide-based polymers, hyaluronic acid, carboxymethyl cellulose and sodium alginate, via electrospinning. The produced nanofibrous mats were crosslinked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. Furthermore, the morphology, in vitro degradation, cytotoxicity and cell adherence potentials of the nanofibrous mats aimed to be used as adhesion barriers were evaluated and compared with a commercial adhesion barrier. Results of the in vitro experiment showed that the nanofibrous mats have maintained their physical structures during the critical period for adhesion formation, and had non-adherent cell feature and non-cytotoxic nature required for an ideal adhesion barrier.", "headline": "In Vitro Evaluation of Electrospun Polysaccharide Based Nanofibrous Mats as Surgical Adhesion Barriers", "identifier": 9969, "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", "license": "http://www.opendefinition.org/licenses/cc-by", "name": "In Vitro Evaluation of Electrospun Polysaccharide Based Nanofibrous Mats as Surgical Adhesion Barriers", "url": "https://aperta.ulakbim.gov.tr/record/9969" }
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