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Safak, Serife; Vatan, Ozgur; Cinkilic, Nilufer; Karaca, Esra
{ "DOI": "10.32710/tekstilvekonfeksiyon.548460", "abstract": "Post-operative adhesions are one of the most important problems faced by patients and surgeons. In this study, nanofibrous mats were produced as novel surgical adhesion barrier from polysaccharide-based polymers, hyaluronic acid, carboxymethyl cellulose and sodium alginate, via electrospinning. The produced nanofibrous mats were crosslinked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. Furthermore, the morphology, in vitro degradation, cytotoxicity and cell adherence potentials of the nanofibrous mats aimed to be used as adhesion barriers were evaluated and compared with a commercial adhesion barrier. Results of the in vitro experiment showed that the nanofibrous mats have maintained their physical structures during the critical period for adhesion formation, and had non-adherent cell feature and non-cytotoxic nature required for an ideal adhesion barrier.", "author": [ { "family": "Safak", "given": " Serife" }, { "family": "Vatan", "given": " Ozgur" }, { "family": "Cinkilic", "given": " Nilufer" }, { "family": "Karaca", "given": " Esra" } ], "container_title": "TEKSTIL VE KONFEKSIYON", "id": "9969", "issue": "2", "issued": { "date-parts": [ [ 2020, 1, 1 ] ] }, "page": "99-107", "title": "In Vitro Evaluation of Electrospun Polysaccharide Based Nanofibrous Mats as Surgical Adhesion Barriers", "type": "article-journal", "volume": "30" }
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