1 Ocak 2020 Dergi makalesi Açık Erişim

Safak, Serife; Vatan, Ozgur; Cinkilic, Nilufer; Karaca, Esra

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/9969</identifier>
  <creators>
    <creator>
      <creatorName>Safak, Serife</creatorName>
      <givenName>Serife</givenName>
      <familyName>Safak</familyName>
      <affiliation>Namik Kemal Univ, Corlu Fac Engn, Dept Text Engn, TR-59860 Corlu, Tekirdag, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Vatan, Ozgur</creatorName>
      <givenName>Ozgur</givenName>
      <familyName>Vatan</familyName>
      <affiliation>Bursa Uludag Univ, Fac Arts &amp; Sci, Dept Biol, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Cinkilic, Nilufer</creatorName>
      <givenName>Nilufer</givenName>
      <familyName>Cinkilic</familyName>
      <affiliation>Bursa Uludag Univ, Fac Arts &amp; Sci, Dept Biol, TR-16059 Bursa, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karaca, Esra</creatorName>
      <givenName>Esra</givenName>
      <familyName>Karaca</familyName>
      <affiliation>Bursa Uludag Univ, Fac Engn, Dept Text Engn, TR-16059 Bursa, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>In Vitro Evaluation Of Electrospun Polysaccharide Based Nanofibrous Mats As Surgical Adhesion Barriers</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2020</publicationYear>
  <dates>
    <date dateType="Issued">2020-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/9969</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.32710/tekstilvekonfeksiyon.548460</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Post-operative adhesions are one of the most important problems faced by patients and surgeons. In this study, nanofibrous mats were produced as novel surgical adhesion barrier from polysaccharide-based polymers, hyaluronic acid, carboxymethyl cellulose and sodium alginate, via electrospinning. The produced nanofibrous mats were crosslinked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. Furthermore, the morphology, in vitro degradation, cytotoxicity and cell adherence potentials of the nanofibrous mats aimed to be used as adhesion barriers were evaluated and compared with a commercial adhesion barrier. Results of the in vitro experiment showed that the nanofibrous mats have maintained their physical structures during the critical period for adhesion formation, and had non-adherent cell feature and non-cytotoxic nature required for an ideal adhesion barrier.</description>
  </descriptions>
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