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Simple high-performance liquid chromatographic method for determination of atropine and obidoxime in a parenteral injection device

Goren, AC; Bilsel, G; Bilsel, M; Yenisoy-Karakas, S; Karakas, D


DataCite XML

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/94623</identifier>
  <creators>
    <creator>
      <creatorName>Goren, AC</creatorName>
      <givenName>AC</givenName>
      <familyName>Goren</familyName>
    </creator>
    <creator>
      <creatorName>Bilsel, G</creatorName>
      <givenName>G</givenName>
      <familyName>Bilsel</familyName>
    </creator>
    <creator>
      <creatorName>Bilsel, M</creatorName>
      <givenName>M</givenName>
      <familyName>Bilsel</familyName>
    </creator>
    <creator>
      <creatorName>Yenisoy-Karakas, S</creatorName>
      <givenName>S</givenName>
      <familyName>Yenisoy-Karakas</familyName>
    </creator>
    <creator>
      <creatorName>Karakas, D</creatorName>
      <givenName>D</givenName>
      <familyName>Karakas</familyName>
    </creator>
  </creators>
  <titles>
    <title>Simple High-Performance Liquid Chromatographic Method For Determination Of Atropine And Obidoxime In A Parenteral Injection Device</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2004</publicationYear>
  <dates>
    <date dateType="Issued">2004-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/94623</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.chroma.2004.09.048</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Atropine and obidoxime in a parenteral injection device are determined by simple HPLC method simultaneously without any pretreatment at 228 nm. The relative standard deviations (R.S.D.) were below 1.6% for the compounds. The correlation coefficient was greater than 0.999 for both compounds in the calibration range. The recoveries at 5 mg/L concentration averaged as 95% for atropine and 102% for obidoxime. The uncertainty of the measurements for atropine and obidoxime was 2.8% and 2.4%, respectively. (C) 2004 Elsevier B.V. All rights reserved.</description>
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