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Simple high-performance liquid chromatographic method for determination of atropine and obidoxime in a parenteral injection device

Goren, AC; Bilsel, G; Bilsel, M; Yenisoy-Karakas, S; Karakas, D


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{
  "DOI": "10.1016/j.chroma.2004.09.048", 
  "abstract": "Atropine and obidoxime in a parenteral injection device are determined by simple HPLC method simultaneously without any pretreatment at 228 nm. The relative standard deviations (R.S.D.) were below 1.6% for the compounds. The correlation coefficient was greater than 0.999 for both compounds in the calibration range. The recoveries at 5 mg/L concentration averaged as 95% for atropine and 102% for obidoxime. The uncertainty of the measurements for atropine and obidoxime was 2.8% and 2.4%, respectively. (C) 2004 Elsevier B.V. All rights reserved.", 
  "author": [
    {
      "family": "Goren", 
      "given": " AC"
    }, 
    {
      "family": "Bilsel", 
      "given": " G"
    }, 
    {
      "family": "Bilsel", 
      "given": " M"
    }, 
    {
      "family": "Yenisoy-Karakas", 
      "given": " S"
    }, 
    {
      "family": "Karakas", 
      "given": " D"
    }
  ], 
  "container_title": "JOURNAL OF CHROMATOGRAPHY A", 
  "id": "94623", 
  "issue": "1-2", 
  "issued": {
    "date-parts": [
      [
        2004, 
        1, 
        1
      ]
    ]
  }, 
  "page": "237-239", 
  "title": "Simple high-performance liquid chromatographic method for determination of atropine and obidoxime in a parenteral injection device", 
  "type": "article-journal", 
  "volume": "1057"
}
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